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Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

TSH is usually the only test needed to check thyroid function in primary care.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

DHT may increase the risk of heart disease and death in elderly men.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Finasteride may cause slight depression and anxiety.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Lower SHBG levels may increase the risk of PCOS.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.