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Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

DHT affects testicular development and regulates spermatogenesis in some fish.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.

The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Possible link between androgens and COVID-19 severity; more research needed.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Skin symptoms can indicate endocrine disorders and have various treatments.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Gut microbes significantly affect brain steroid levels.

Diet changes can protect against harmful environmental effects on fetal development.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

A woman with acromegaloidism and normal growth hormone levels had a rare X-Tetrasomy, suggesting a need to study X-chromosome genes for their role in growth and facial development.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.