6 citations
,
August 2020 in “International Research Journal on Advanced Science Hub” In this study, researchers developed a niosomal gel system for transdermal delivery of testosterone, reporting strong penetrative capability, good spreadability, and a promising in vitro drug release profile, suggesting it may be an effective alternative for reducing the side effects of steroid treatments.
39 citations
,
March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that GLI2 plays a key role in activating follistatin, an activin/BMP antagonist, in response to hedgehog signaling in human epidermal cells, with implications for hair follicle development and basal cell carcinoma.
29 citations
,
July 2008 in “British Journal of Dermatology” This case report examines a patient with myasthenia gravis, invasive thymoma, and paraneoplastic pemphigus associated with alopecia areata, notably without the usual mucosal involvement.
November 2025 in “Journal of Investigative Dermatology” BTNL2 helps protect hair follicles from immune attacks.
8 citations
,
January 2023 in “International journal of molecular sciences” This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.
13 citations
,
October 2020 in “BMC Genomics” This study revealed specific patterns and potential functions of long non-coding RNAs during the hair follicle cycle of yaks, offering insights into their sequence conservation between yaks and cashmere goats.
4 citations
,
March 2007 in “British Journal of Dermatology” This case report observed that terminal hair growth on the nose tip was associated with gefitinib treatment in a 65-year-old woman with lung adenocarcinoma.
April 2018 in “Journal of Investigative Dermatology” This study suggests that human hair follicles may operate their own Cori cycle, synthesizing glycogen from lactate under conditions of lactic acidosis.
5 citations
,
September 2015 in “PLoS ONE” This study demonstrated that Gelfoam® histoculture supports extensive growth of both hair shafts and sensory nerves from isolated mouse whisker follicles over prolonged periods.
June 2025 in “Proceedings of the National Academy of Sciences” In this study, a mouse model with a PIK3CA gain-of-function mutation in Schwann cells revealed unique communication with neighboring cells and a glycolytic shift in peripheral nerves, and early alpelisib treatment significantly improved symptoms, though efficacy declined with delayed administration due to limited drug penetration.
10 citations
,
June 2021 in “Journal of Investigative Dermatology” GNPTAB gene is crucial for normal hair color in humans and mice.
July 2026 in “Dermatology and Therapy” In this study, women experiencing hair thinning who consumed tailored botanical-based nutraceuticals saw significant increases in linear hair growth rate and other hair health parameters over 90 and 180 days, supporting their effectiveness across different life stages.
This research found that nod factor can induce root hair reorientation and gene expression in Medicago truncatula with as little as a single molecule, implicating heterotrimeric G-protein signaling in this process.
September 2025 in “Development” In this study, deleting the transcriptional pause factor Nelfb in mouse preadipocyte lineages led to defective dermal fat formation and lethal outcomes, while interventions targeting Pparg could rescue adipocyte differentiation and promote dermal white adipose tissue formation, underscoring Nelfb's critical role in adipogenesis.
3 citations
,
January 2021 in “Applied sciences” This study found that in C57BL/6 mice, treatment with fermented red ginseng marc, a traditional polyherb formula, or a combination of both, promoted hair growth by enhancing the hair-growth cycle.
119 citations
,
June 2021 in “Heliyon” This review examines the phytochemical constituents and pharmacological effects of licorice, discussing its potential health benefits and side effects without reporting new clinical results.
2 citations
,
December 2013 in “The Journal of Dermatology” This article is a letter to the editor about onychogryphosis associated with an elastic wire, and reports no new research findings.
May 2015 in “Journal of The American Academy of Dermatology” The Nd:YAG laser is a successful and safe way to treat ingrown and pincer nails.
September 2025 in “Genes & Diseases” This study explores the role of Lgr6+ cells in tissue development and repair across different organs and associates abnormal Lgr6 expression with major diseases, including tumors, noting its potential as a therapeutic target for cancer and other conditions.
January 1998 in “The Nishinihon Journal of Dermatology” A 7-year-old girl was diagnosed with Netherton's Syndrome, shown by skin and hair symptoms.
This study found that GPC1 is a significant regulator of angiogenesis in human dermal microvascular endothelial cells, suggesting its potential as a target for alopecia research.
17 citations
,
June 2017 in “Gene” This is the first report of the FOXN1 p.R255X mutation from India, demonstrating the global spread of this genetic mutation previously found only in an Italian community.
November 2012 in “Experimental and Clinical Endocrinology & Diabetes” This case report describes a 46,XY female patient with a novel homozygous nonsense mutation in the LHCGR gene, highlighting the need for molecular analysis in disorders of sexual development.
This study found that GPC1 is a key regulator of angiogenesis in human dermal microvascular endothelial cells, influenced by factors secreted by keratinocytes, and may be a target for alopecia treatment research.
October 2025 in “Advanced Healthcare Materials” In a study on wound healing, researchers described injectable POEGMA‐DA hydrogels as a promising non-toxic alternative to traditional wound closure methods, showing effective tissue adhesion and enhanced regeneration of skin structures in a mouse model without significant inflammation.
This study found that GPC1 is a key regulator of angiogenesis in hair follicles and may be an interesting target for addressing alopecia in dermatology research.
February 2022 in “The Nurse Practitioner” This article provides an introduction to gender-affirming hormone therapy for transgender and gender-nonbinary patients, designed as a continuing education activity, but does not report new clinical results.
March 2025 in “OncoTargets and Therapy” This study found that in circulating tumor cells from non-invasive liquid biopsies, the GG genotype of the CYP3A5 A6986G affects longer disease-free survival in DLBCL patients, highlighting the significance of circulating biomarkers for prognostic evaluation.
June 2025 in “International Journal of Molecular Sciences” This review compiles current research on the role of long non-coding RNAs in regulating muscle growth and regeneration processes, particularly their influence on Duchenne muscular dystrophy, and reports no new clinical results.