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This review found that women with idiopathic hirsutism may have increased 5α-reductase activity, as indicated by elevated levels of a dihydrotestosterone-reduced metabolite, but more research is needed to confirm its clinical relevance as a biomarker.

This study found that serum 3 alpha-diol G levels in women with idiopathic hirsutism correlated well with their clinical response to treatment, suggesting its usefulness in evaluating treatment outcomes.

This study suggests 5α‐androstan‐3α‐17β‐diol may be the true inducer of kidney enzymes in certain mice, while its induction mechanism likely involves pinocytosis rather than a receptor protein.

This study found that patients with decreased kidney function had significantly higher hair levels of ethyl glucuronide compared to healthy individuals, suggesting these results should be cautiously interpreted.

This study identified a series of novel β-glucuronidase inhibitors that may help mitigate adverse effects of first-line anti-cancer drugs by targeting gut bacteria, based on virtual high-throughput screening findings.

This study found that exposure to artificial sunlight led to variable changes in ethyl glucuronide levels in hair, with both increases and decreases observed depending on hair characteristics.

This study found that plasma 3 alpha-diol glucuronide was markedly elevated in women with idiopathic hirsutism, suggesting it may be a marker of peripheral androgen action.

The researchers reported that glucuronides stored as dried blood spots under ambient conditions exhibited stability equivalent to liquid samples stored at -80°C.

This study found that serum 3 alpha-Adiol-G levels in men are significantly associated with chest hair density and acne, indicating its role in reflecting androgen activity in peripheral tissues.

This study found that in women with acne vulgaris, lower serum levels of 3α-androstanediol-glucuronide suggest reduced 5α-reductase activity compared to controls, indicating that 5α-reductase inhibitors may not be effective for acne treatment.

This study found that serum 3α-androstanediol glucuronide levels were higher in Indian women with female pattern hair loss and correlated with the severity of the condition.

In this study, researchers found that while chest hair can be a reliable alternative to scalp hair for ethylglucuronide testing, seasonal factors may affect concentration levels and should be considered in result interpretation.

The authors concluded that plasma levels of 3α-diolG, ADTG, and DHTG in women with hyperandrogenic disorders primarily reflect adrenal androgen contributions rather than peripheral action, suggesting a potential index for treatment effectiveness.

This study found that women with female pattern baldness often had a higher ratio of 3 alpha,17 beta-androstanediol glucuronide to sex hormone-binding globulin and lower serum sex hormone-binding globulin, possibly indicating minimal androgen excess.

This study concluded that serum Adiol-G levels generally parallel testosterone levels and, therefore, do not effectively serve as a marker of peripheral androgen excess in women with androgenic symptoms.

This study identified previously unknown phase I and phase II metabolites of finasteride in human bile and urine using a specialized bile collection technique and advanced mass spectrometry analysis.

This study developed and validated a comprehensive method using mass spectrometry to profile sex (pro)hormones in plasma, with results showing reliable calibration and detection of 31 analytes in samples from pre- and postmenopausal women and men, while addressing potential over- or underestimations in analyte concentrations.

This study found that the metabolic profile of finasteride in pigs closely matches that of humans, supporting the use of pigs for studying human drug metabolism.

Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.

This study found that girls with prepubertal simple hypertrichosis had significantly higher plasma levels of dihydrotestosterone compared to controls, which does not align with other androgen markers and warrants further investigation.

This study analyzed the geometric and electronic properties of baicalin conformers, finding that BCLa2TT and BCLa1TT conformers exhibit high stability in aqueous solutions and are favorable for interactions with positively charged species.

This study in humans and pigs found that finasteride metabolism is significantly influenced by CYP3A4, with induced metabolism decreasing and inhibited metabolism increasing plasma exposure of the drug.

This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.

This article provides citations without reporting new findings on androgen conjugate levels in alopecia.

This review discusses the use of anabolic-androgenic steroids in sports and outlines current methods for detecting urinary steroid doping, particularly testosterone, but reports no new experimental findings.

This review discusses the importance of androgen production and metabolism in hyperandrogenism, the use of specific serum markers for diagnosis, and the need for improved assays for clinical testing, but reports no new results.

This review examines the physiological role of androgen conjugates in cutaneous androgen metabolism and questions their association with hirsutism, without presenting new clinical findings.

This article reviews the role of 5α-reductase in cutaneous hyperandrogenism and the potential of 5α-reductase inhibitors and antiandrogens in treating conditions like hirsutism and male-pattern baldness, reporting no clinical results.

This review describes how liver and kidney diseases and diabetes may affect ethyl glucuronide levels in hair, impacting forensic and clinical interpretations, but reports no new experimental results.