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Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

BMP2 and BMP7 have opposite roles in feather formation.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

HFMs can help study hair growth and test potential hair growth drugs.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Improving the environment and cell interactions is key for creating human hair in the lab.