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Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Diane 35 plus finasteride is more effective for treating hirsutism.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

DHT, a testosterone byproduct, causes male pattern baldness.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Spironolactone plus finasteride reduces hirsutism more effectively.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Prolactin may be important for skin growth and immune function.

Certain hormone treatments can improve acne and related conditions in women.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.