277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
99 citations,
August 2009 in “Nature Genetics” Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
33 citations,
November 2006 in “Survey of Ophthalmology” Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.
60 citations,
September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
5 citations,
February 2022 in “Acta Biomaterialia” Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.
69 citations,
February 2008 in “The American journal of pathology” Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
51 citations,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
January 2023 in “Vìsnik problem bìologìï ì medicini” Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
12 citations,
October 2004 in “Experimental Gerontology” Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.
117 citations,
August 2019 in “Drug Design Development and Therapy” Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.
59 citations,
September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
January 2009 in “Springer eBooks” The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.
June 2015 in “Journal of the turkish academy of dermatology” Eating the right foods is important for skin health and can help treat some skin conditions.
29 citations,
May 2018 in “Clinical Endocrinology” Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
7 citations,
November 2018 in “British Journal of Dermatology” Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.
240 citations,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
185 citations,
August 2005 in “Autoimmunity Reviews” Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
41 citations,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
9 citations,
December 2017 in “The Journal of Allergy and Clinical Immunology” New targeted therapies for hair loss from alopecia areata show promise, with personalized treatment expected in the future.
421 citations,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
30 citations,
December 2001 in “Experimental dermatology” Gonadal hormones significantly affect the severity of alopecia areata in mice.
24 citations,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
3 citations,
September 2023 in “Frontiers in immunology” Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
22 citations,
November 2016 in “International journal of molecular sciences” Vitamin D receptor is important for regulating hair growth and wound healing in mice.
43 citations,
December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
91 citations,
January 2010 in “Journal of Allergy and Clinical Immunology” NK cells play a role in skin diseases like eczema and psoriasis.
1 citations,
January 2014 in “Hair therapy & transplantation” Platelet-rich plasma treatment is not very effective for chronic severe alopecia areata.
120 citations,
November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
50 citations,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.