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Genetic mutations can affect female sexual development, requiring personalized medical care.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Genes and hormones cause hair loss, with four genes contributing equally.

Sex-determining genes may affect male baldness.

A man with KID syndrome developed a rare cancer in a long-term skin infection.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Plant hormones have potential in agriculture to increase food production but require more research for effective use.

New genes and pathways are important for testosterone production and male sexual development.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

DHT affects testicular development and regulates spermatogenesis in some fish.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.