1 citations
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November 2005 in “Journal of Andrology” This meeting abstract details various lectures and workshops from the 30th Annual Meeting of the American Society of Andrology, including findings on genetic and physiological factors affecting male fertility, but reports no new clinical results.
April 2015 in “Experimental Dermatology” Melanoma risk tools need improvement, certain gene mutations cause skin diseases and could be treated by targeting those mutations, skin wrinkling may relate to lung aging due to genetic factors, and oxidative stress affects hair loss but can be reduced in low oxygen.
151 citations
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November 2014 in “Annual Review of Animal Biosciences” This review discusses three decades of progress in feather development, regeneration, and evolution, with no new experimental results; it highlights feathers' potential as a model for morphogenesis studies.
11 citations
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October 2019 in “Cancers” This study found that spironolactone enhanced the effectiveness of non-DNA-damaging cancer drugs gemcitabine and osimertinib in cancer cell lines and a mouse xenograft model, likely by suppressing the anti-apoptotic protein survivin.
10 citations
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December 1991 in “Annals of the New York Academy of Sciences” This study found that minoxidil increases the expression of a reporter gene linked to hair growth in cultured hair follicles from transgenic mice, suggesting a potential model for studying hair biology.
February 2026 in “SHILAP Revista de lepidopterología” This study found that a family history of androgenetic alopecia and specific trichoscopic features are key factors in predicting female pattern hair loss, and the developed nomogram model may help improve disease management by assessing these risks.
27 citations
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January 2000 in “Developmental Dynamics” This study reports that a new nude allele, nu(StL), encodes a truncated Whn transcription factor affecting T-cell development and keratin gene expression, with notable differences from the original Whn(nu) mutation.
35 citations
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April 2008 in “Journal of Biological Chemistry” This study found that the lack of expression and deletion of specific hair keratin genes on chromosome 7q36 in Hirosaki hairless rats suggests the crucial role of these genes in hair growth.
4 citations
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January 2025 in “Molecules and Cells” This guide provides essential information for researchers working with laboratory mice, including husbandry, maintenance, ethical considerations, and resources for strains and data, emphasizing the importance of the 3Rs (replacement, reduction, and refinement) for humane research practices.
16 citations
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January 2015 in “Genetics and Molecular Research” This study conducted de novo transcriptome sequencing in sheep skin, identifying and annotating numerous unigenes, which may aid in improving wool quality and understanding hair follicle development.
October 2018 in “Current Opinion in Genetics & Development” The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.
189 citations
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July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” This review discusses how research on keratin biology has enhanced the understanding of epidermolysis bullosa simplex and indicates potential new therapeutic approaches, but it presents no new experimental results.
March 2024 in “Jagiellonian University Repository (Jagiellonian University)” This study found that DNA methylation-based age predictors and lifestyle factors significantly affect perceived age and external visible characteristics in the aging process, with implications for forensic and anti-aging cosmetic applications.
17 citations
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July 2017 in “Molecular and Cellular Endocrinology” The authors reviewed the mechanisms behind Kennedy's disease, noting advances in therapeutic strategies such as androgen deprivation and gene silencing that may soon expand treatment options for this incurable neuromuscular condition.
9 citations
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July 2021 in “Dermatology and Therapy” This review highlights promising recent advances in therapies for epidermolysis bullosa, including gene therapy and stem cell approaches, but reports no definitive cures and emphasizes the need for further research.
November 2025 in “Journal of Investigative Dermatology” KLHL24-mutant stem cells help understand skin and heart disease.
25 citations
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June 1998 in “Journal of Investigative Dermatology” Murine cytomegalovirus does not cause alopecia areata in these mice.
3 citations
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June 2020 in “Frontiers in Immunology” This mouse study found that offspring of parents with uveitis showed increased susceptibility to experimental autoimmune uveitis, potentially due to altered immune and cellular processes.
109 citations
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January 1997 in “Journal of Experimental Botany” This paper discusses the cellular and molecular processes involved in root hair growth in higher plants, focusing on cytological phenomena and the effects of growth regulators and mutations, but reports no new experimental findings.
3 citations
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April 2022 in “Biomolecules” This study found that the MIR34A rs2666433 (A/G) variant is linked to increased risk and severity of alopecia areata, and high circulatory miR-34a levels may play a role in the disease's pathogenesis.
February 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in adult mouse skin, somatosensory axon plasticity is highly dynamic and influenced by epithelial-neural crosstalk and intrinsic neural mechanisms.
351 citations
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February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
124 citations
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June 2020 in “Cell Stem Cell” This study found that in mice, dermal adipocytes initiate inflammation and aid repair after skin injury by releasing lipids, suggesting a role in managing inflammatory diseases and impaired wound healing.
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study suggests that typical skin lesions in Carney complex may originate from the pro-melanogenic activity of a specific dermal fibroblast population influenced by PKA signaling.
143 citations
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May 2017 in “Nature cell biology” This study found that the transcription factor Gata6 regulates the sebaceous duct lineage identity and plays a crucial role in epidermal wound healing by enabling dedifferentiation and broader lineage capabilities in post-mitotic cells.
40 citations
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November 2021 in “International Journal of Molecular Sciences” This review highlights the role of keratin mutations in epidermolysis bullosa simplex and the resulting chronic inflammation, but it presents no new experimental findings.
5 citations
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September 2022 in “Research Square (Research Square)” This study identified CD201+ fibroblast progenitors in mouse skin that regulate wound healing through differentiation into specialized cell types, with retinoic acid and hypoxia influencing this process.
April 2023 in “Journal of Investigative Dermatology” This study identified a new role for IL-4Ra-induced oxidative metabolism in wound macrophages, essential for balancing inflammatory response and promoting pro-fibrotic repair, suggesting a target for fibrosis prevention.
January 2014 in “International Journal of Clinical Medicine” This case report suggests that premature aging may contribute to weakened immunity and the development of autoimmune diseases.
April 2021 in “Journal of Investigative Dermatology” Blocking DPP4 can help prevent fat loss and skin fibrosis.