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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Common variants in the Trichohyalin gene are linked to straight hair in Europeans.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

A genetic mutation in the LIPH gene causes hair loss and growth defects.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Women with PCOS have lower quality of life, especially in mental health and energy, and managing weight can help improve it.

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Humans lost body hair relatively recently in evolution.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.

Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Forehead modification greatly increases the perception of femininity and is a safe procedure.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

EGFR is essential for normal hair development and follicle differentiation.