61 citations
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January 2007 in “Indian Journal of Dermatology Venereology and Leprology” This study found that garlic gel significantly improved the efficacy of topical betamethasone valerate in treating alopecia areata compared to placebo.
7 citations
,
December 2021 in “Pharmaceutics” This study developed a nanoemulsion of garlic oil and apple cider vinegar loaded with minoxidil to enhance drug permeation through skin, reporting improved ex vivo skin permeation parameters compared to an aqueous dispersion of minoxidil, suggesting potential benefits for treating alopecia areata.
4 citations
,
January 2006 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that garlic gel can significantly stimulate hair growth in patients with alopecia areata after three months of treatment.
3 citations
,
October 2021 in “Journal of Cosmetic Dermatology” This study found that topical patches containing allicin from garlic extract may be a promising and cost-effective option for treating alopecia areata, offering better aesthetic acceptance than mashed garlic.
1 citations
,
January 2022 in “Journal of Drug Delivery Science and Technology” This study found that a nanotransferosome formulation of finasteride (FI-GO-NTF) in an Aloe vera gel significantly improved scalp permeation and antibacterial activity compared to standard formulations, suggesting safe and effective potential for alopecia areata treatment.
May 2026 in “VT International Press Journal of Multidisciplinary Research and Review” This study developed a herbal hair oil using garlic leaves, coconut oil, castor oil, hibiscus flower powder, and amla extract, finding it enhances scalp nutrition, reduces hair loss, and maintains favorable aesthetic attributes with appropriate stability and consistency for hair application.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated polyherbal formulations for managing hair issues such as dandruff, dryness, premature greying, baldness, and hair fall, but it reports no new clinical results.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study assesses the effectiveness of polyherbal formulations in managing hair issues such as dandruff, dryness, premature greying, baldness, and excessive hair fall, in response to increasing hair loss among younger individuals due to stress, poor diet, and chemical use.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review assesses the potential of ginger, garlic, onion, and clove as complementary herbal treatments for hair and scalp health, reporting that onion juice shows the strongest clinical evidence for hair regrowth, particularly in alopecia areata, while garlic exhibits promising preclinical regenerative effects.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review evaluates herbal botanicals like onion, garlic, ginger, and clove for hair and scalp health, noting that onion juice shows the strongest clinical evidence for hair regrowth particularly in alopecia areata, although these cannot replace traditional medical treatments.
This study found that garlic exosomes induced hair growth in rats by increasing anagen follicle counts and activating multiple signaling pathways, including Wnt-1, β-catenin, and TGF-β1.
13 citations
,
April 2025 in “International Journal of Nanomedicine” In this study, a hydrogel with anti-inflammatory, antibacterial, antioxidant, and wound tissue adhesion properties was developed, showing significant potential for wound healing and suggesting it could offer a new and effective treatment option in clinical settings.
4 citations
,
March 2023 in “Molecules/Molecules online/Molecules annual” This study successfully extracted gallic acid and ferulic acid using a biocompatible aqueous two-phase system, suggesting a sustainable approach for producing antioxidants as food supplements for hair health.
November 2024 in “Apple Academic Press eBooks” In this chapter, the authors emphasize the significant therapeutic roles attributed to Allium tuberosum due to its rich phytochemicals, detailing potential benefits against various conditions like diabetes, cancer, and liver dysfunction, as well as its applications in anticoagulation, muscle cell proliferation, and sensory perception mediation.
4 citations
,
January 1994 This article reviews the consumption patterns and historical use of Allium vegetables like onions and garlic for their potential antimicrobial and cardiovascular benefits, but reports no new clinical findings.
January 2024 in “International Journal of Environment Agriculture and Biotechnology” In this study, organic garlic was found to have higher levels of bioactive elements and stronger antimicrobial properties compared to chemically grown garlic, highlighting the benefits of organic cultivation for enhancing garlic's nutritional and health-promoting qualities.
91 citations
,
May 2023 in “Journal of Cutaneous Medicine and Surgery” Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.
67 citations
,
July 2011 in “Clinical, cosmetic and investigational dermatology” This review discusses various therapeutic agents for alopecia areata, categorized by efficacy and safety, and highlights the lack of curative treatments and long-term outcome studies.
40 citations
,
August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
25 citations
,
May 2009 in “International Journal of Dermatology” This study found that 33.5% of dermatology outpatients in Turkey used unconventional therapies, with no significant differences based on age, sex, or education.
24 citations
,
January 2020 in “International Journal of Molecular Sciences” This review discusses the potential benefits of flavonoid-containing botanicals, such as Panax ginseng, in reducing hair loss and promoting hair growth, but reports no new experimental results.
17 citations
,
February 2015 in “Phytochemistry Reviews” This review discusses the cosmetic potential of Southeast Asian herbs and highlights the need for more systematic scientific evaluation of their efficacy and safety.
15 citations
,
December 2009 in “American journal of clinical dermatology” The effectiveness of alternative treatments for alopecia areata is uncertain and needs more research.
14 citations
,
October 2020 in “Natural Products and Bioprospecting” This review discusses current topical treatments, natural products, and complementary therapies for androgenetic alopecia, but it reports no new clinical results.
11 citations
,
April 2025 in “Pharmaceutics” In this review, researchers explore various treatment options for alopecia, focusing on nano-drug delivery systems using plant-based substances, which are potentially effective and less harmful than current treatments, while also highlighting emerging trends such as 3D bioprinting and plant extracts for future therapies.
10 citations
,
May 2018 in “Nutrition and Cancer” This article reviews current research on spice-derived nutraceuticals for treating melanoma and skin cancer, noting emerging evidence that these natural substances may offer preventative and protective benefits against cancer, amidst increased global interest.
9 citations
,
March 2011 in “Oxidative stress and disease” This review explores herbal medications for skin disorders, covering their clinical efficacy, safety, and common drug interactions, but reports no new clinical results.
7 citations
,
January 2018 in “Asian journal of pharmaceutical research” In this study, the authors reviewed the importance of a polyherbal hair oil containing ingredients like Amla and Neem, evaluated for properties like pH and viscosity, but effectiveness for treating hair issues such as dandruff and baldness is not reported.
4 citations
,
January 2021 in “DergiPark (Istanbul University)” This review details 171 plant taxa traditionally used in Turkey to treat boils, but reports no new clinical results; the authors assess the literature on biological activities of commonly used genera like Allium and Brassica.
3 citations
,
February 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study suggests that a herbal oil formulation combining various plant and oil ingredients may effectively promote healthy hair growth and address concerns like baldness, dryness, and dandruff, supported by favorable evaluations of its physical and chemical properties.