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IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

CD4+ skin cells may be precursors to basal cell carcinoma.

Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Mice with autoimmune hair loss showed signs of heart problems.

Paeonia lactiflora and Poria cocos extracts can potentially increase hair growth and reduce hair loss symptoms by lowering testosterone and inflammation levels.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The document suggests a rare skin condition might be caused by a genetic phenomenon.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Hair follicles can be used to quickly assess drug effects in cancer treatment.