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This study developed a potent Wnt surrogate with high specificity for the Fzd7 receptor in mice, promoting full hair follicle regeneration and robust hair growth, suggesting potential applications in tissue development and targeted regeneration.

Skin-derived stem cells could help treat skin aging and pigmentation issues.

This study revealed that frizzled 3 can fully rescue polarity defects in frizzled 6-null mice, while frizzled 6 can partially rescue defects in frizzled 3-null mice, highlighting conserved signaling roles in these proteins.

This study found that super-enhancers are essential for hair follicle stem cell identity, lineage commitment, and plasticity in mice, with SOX9 being a key regulator of these chromatin dynamics.

This study found that induced expression of mir-302 can reprogram human hair follicle cells into induced pluripotent stem cells through a novel epigenetic mechanism involving global demethylation.

This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.

This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.

This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.

This review discusses the role of Wnt/β‐catenin signaling in stem and cancer stem cell maintenance and its involvement in the development and regeneration of various organs, but reports no new experimental results.

This review summarizes recent findings on how Wnt signaling proteins play crucial roles in the cutaneous wound healing process but reports no new clinical results.

In this review, the researchers detailed how the p63 transcription factor influences epithelial stem cell activities such as self-renewal, differentiation, and proliferation, highlighting the role of TAp63 and ΔNp63 isoforms in both normal tissue development and cancer pathogenesis.

In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.

In this study, researchers found that intestine-derived human alpha defensin 5 enhances wound healing, reduces bacterial load, and promotes hair growth in murine burn wound beds by increasing LGR stem cell migration.

This study provides new insights into the identification and expression patterns of miRNAs in wool follicles, which could improve understanding of wool follicle development in sheep.

This study sequenced and analyzed the goat skin transcriptome, revealing genes involved in signal transduction and cell communication that are differentially expressed during hair growth phases, providing insights for Cashmere goat breeding.

This study found that Wnt3a increased beta-catenin signaling and upregulated specific genes in cultured human dermal papilla cells, enhancing their response to PGE2 and potentially aiding hair growth.

This review highlights the potential of natural product-derived compounds, such as flavonoids and alkaloids, to reverse multidrug resistance in tumors, emphasizing their role in regulating signaling pathways, proteins, and genes related to MDR, and aims to guide future research efforts in this area.

This review explores regenerative medicine approaches for vitiligo and alopecia areata, focusing on pathways for repopulating melanocytes and regrowing hair follicles, and summarizes potential treatments without reporting new clinical results.

This study in cashmere goats found that DNA methylation levels were lower during hair follicle differentiation compared to induction, suggesting it plays a critical role in gene regulation for hair morphogenesis.

This review discusses the interactions between melanocyte stem cells and their niche in hair regeneration and repair, but reports no new results; recent studies on molecular pathways are highlighted.

This article reviews the roles and mechanisms of stem and progenitor cell migration in adult organs for tissue homeostasis and regenerative medicine, but reports no new experimental results.

This study found that bovine lactoferrin promotes hair growth in mice by enhancing dermal papilla cell proliferation through the Erk/Akt and Wnt signaling pathways.

The researchers reported that minor salivary gland stem cells exhibit stem cell characteristics and respond to tobacco-derived carcinogens, implicating the transforming growth factor beta pathway in their maintenance.

The researchers found that HOXC13 regulates different keratin proteins in a mixed manner, with certain SNPs impeding this regulation, while also demonstrating negative-feedback by HOXC13 and positive regulation by LEF1 and melatonin on the HOXC13 promoter.

This review discusses the varied roles of Wnt7a in development, tissue homeostasis, and cancer, reporting no clinical results; the authors emphasize the need for further investigation on its roles in inflammation and fibrosis.

This study reported that pathways related to apoptosis, cell proliferation, and WNT signaling might be key drivers of hair loss in androgenetic alopecia, guiding potential targets for therapy development.

This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

This study revealed that Vav2 and Vav3 play roles in regulating hair follicle bulge stem cells in normal conditions and cancer stem cell activation and remodeling in mice.

This study developed a culture method to expand and differentiate primary mammary basal cells, identifying key transcription factors like EGR1 and ELF3 that influence Claudin expression and actin organization, offering insights into epithelial cell biology and potential applications in related research fields.