Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, pediatric patients with alopecia areata treated with systemic tofacitinib showed significant improvement at 12 months, but the small sample size and retrospective design limit conclusions about its effectiveness.

This study found that dermoscopy combined with calcium fluorescent white staining effectively aided in the early diagnosis and treatment evaluation of tinea capitis by highlighting specific hair changes and fluorescent patterns associated with different dermatophyte infections in a sample of 20 patients.

This study found that tofacitinib significantly improved disease activity in most patients with LPP, though further research is needed to refine protocols, understand response predictors, and address gender-specific adverse effects.

This study used fibre optic confocal imaging to visualize subsurface structures in live mouse skin, revealing cellular details and blood vessel networks that dynamic events could be studied in vivo.

This study found that frontal fibrosing alopecia involves distinct molecular changes, such as downregulation of steroid and cholesterol pathways and upregulation of fibrotic and immune response genes, which may help guide treatment strategies.

This paper reviews the use of interferons, particularly alfa interferon, in treating cutaneous T-cell lymphoma, noting its substantial efficacy both alone and in combination therapies with predictable, generally well-tolerated side effects.

This study found that a single 2 ml injection of TEEV every 4 weeks offers similar beneficial effects with fewer side effects compared to injecting the same dose every 2 weeks in postmenopausal women.

This study found that tofacitinib was an effective and better-tolerated treatment for moderate-to-severe AA compared to SCs, though its efficacy decreased in patients with disease episodes longer than two years.

This study mapped the safety profile of EGFR-TKIs by analyzing FDA adverse event reports, highlighting unexpected reactions like intestinal obstruction and hypokalaemia with gefitinib and erlotinib.

This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets, requiring conversion to DHT and E2 via SRD5A1 and aromatase.

The researchers reported that they successfully developed and validated RP-HPLC and TLC methods for accurately measuring tamsulosin hydrochloride and finasteride in combination forms.

This case study describes a previously unknown association of the PIBIDS complex with autoimmune thyroiditis and autoimmune hemolytic anemia in a five-year-old Indian child.

This study suggests that topically applied fusidic acid may penetrate only the most superficial layers of canine skin but can reach sufficient concentrations to potentially treat infections caused by pathogenic staphylococci.

This study presents a validated questionnaire, the FFA-QLI, which effectively assesses and differentiates the quality of life impact among patients with frontal fibrosing alopecia, showing greater sensitivity in identifying severe cases than the DLQI.

In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.

This article discusses the features and increasing prevalence of frontal fibrosing alopecia, a type of scarring hair loss, and reports no new clinical results.

This study analyzed 3,295 cases from the FDA Adverse Event Reporting System to describe demographics and reporting trends of post-finasteride syndrome, finding that most reports came from patients rather than health professionals.

This study found that finasteride gel 0.25% significantly decreased hair growth in women with idiopathic hirsutism over six months without any reported side effects.

This study found that two eco-friendly analytical methods for quantifying Finasteride and Tadalafil in a new dosage form were effective, green, and suitable for quality control.

This article reviews the development of follicular unit transplantation for hair replacement, highlighting its ability to provide natural-looking results with minimal recovery time, but results depend heavily on the skill and planning of the practitioner.

This study comprehensively compared different crystalline forms of finasteride, including the new finasteride DMF solvate hemihydrate, to better understand their structural characteristics and intermolecular interactions.

In this ex vivo and mouse model study, Tofacitinib-loaded nanoparticles demonstrated enhanced delivery of the drug into hair follicles and reduced inflammatory effects compared to conventional forms, indicating potential for safer, topical use in treating alopecia areata.

In this study, patients with specific skin and scalp conditions, including eczematous lesions, showed significant improvement after two weeks of oral tofacitinib treatment, as evidenced by changes in the trunk lesions.

This study suggests that folliculin, mutated in Birt–Hogg–Dubé syndrome, and its partner FNIP1 may play a role in energy and nutrient sensing through the AMPK and mTOR pathways.

This study examined the therapeutic response to folliculitis decalvans treatments among 60 patients and found that earlier disease onset was linked to more severe cases, while a combination of rifampicin, clindamycin, tetracyclines, and intralesional steroids was most effective in controlling symptoms.

This case report presents three sisters with familial frontal fibrosing alopecia, making it the 25th documented familial case, with treatment results observed in one sister.

This study reported six pediatric cases of temporal triangular alopecia and highlighted the use of trichoscopy to distinguish it by detecting a distinctive carpet of vellus hair, helping to differentiate TTA from other hair loss conditions.