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This study reviewed 38 cases of frontal fibrosing alopecia, observing that diagnosis often occurs years after onset and is more prevalent in postmenopausal women.

This study suggests that decreased SHBG levels and increased FAI, free testosterone, and DHEAS concentrations are effective in diagnosing PCOS in epidemiological studies of women of reproductive age.

This review provides a detailed analysis of frontal fibrosing alopecia, focusing on its prevalence in postmenopausal Caucasian women, associated comorbidities, and potential autoimmune, genetic, hormonal, and environmental factors; it emphasizes the need for improved understanding to enhance diagnosis and treatment.

This study found that SDR5A1 gene expression was similar between hirsute women, normal women, and men, suggesting it may not explain differences in hair growth among these groups.

This review discusses frontal fibrosing alopecia and reports no clinical results; the authors note that no therapeutic options tested, including corticosteroids, finasteride, and minoxidil, have shown clear benefits.

This study found that a modified Ferriman-Gallwey score of 11 may be appropriate for diagnosing hirsutism in Turkish women, but should be adjusted based on individual factors like age, skin type, and family history.

This article involves an interview with dermatologist Rodney Sinclair and provides no new research findings.

This study found that all-trans and 9-cis retinoic acids increase steroid sulfatase activity in HL60 cells through mechanisms involving RARα/RXR heterodimers and multiple signaling pathways.

In this study, patients with testicular feminization syndrome showed limited anabolic responsiveness to dihydrotestosterone, potentially due to reduced affinity of nuclear receptor sites for androgenic steroids rather than defective testosterone conversion.

Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.

This review discusses the physiology and potential hormonal mechanisms involved in female pattern hair loss, as well as the current hormonal and hormone-modifying treatments available, but reports no new research findings.

This study discovered that TTR is expressed in the human placenta as early as 6 weeks gestation, with increased levels in the first trimester potentially facilitating thyroid hormone delivery to the fetus.

This review suggests that finasteride is well-tolerated and potentially more effective than other treatments for hirsutism, with results confirmed by other studies.

In this study, FMN was found to inhibit androgen receptor function and androgen-regulated gene expression in prostate cancer cells, suggesting potential as an antiandrogen therapy.

This notice announces the upcoming 22nd ISHRS Annual Scientific Meeting, highlighting it as a key event for hair restoration surgeons to learn about recent innovations; it reports no new results.

This study found that the combination of cyproterone acetate and ethinyl estradiol improved hirsutism and acne in women, with SH 8.1041 showing significant results and both treatments being generally well-tolerated.

In this study, facial feminization surgeries were found to be effective and generally safe, significantly enhancing feminine appearance in patients, with minimal major complications reported.

In this study, a modified Ferriman-Galwey score greater than 4 was found to be effective for diagnosing hirsutism in Asian women, highlighting key areas such as the upper lip, thighs, and lower abdomen.

This study found that recombinant human HGF/SF injections altered hair follicle growth cycles and mildly promoted hair elongation in mice, depending on their hair cycle stage.

This review highlights current treatment options for frontal fibrosing alopecia, noting that 5-α-reductase inhibitors, intralesional steroids, and hydroxychloroquine have the highest evidence of effectiveness, while other therapies show variable results and need further research.

Results are not reported in the provided abstract, which issues an expression of concern regarding a 1997 article published in Gynecological Endocrinology.

This study reported that prompt diagnosis and treatment with 5-alpha-reductase inhibitors and topical immunomodulators are key to mitigating the effects of frontal fibrosing alopecia and preventing permanent hair loss.

This study found that pubic skin fibroblasts respond to androgens, increasing 5α-reductase activity via an androgen receptor-mediated mechanism, suggesting its potential as a marker of androgen action in vitro.

This review discusses changes and advancements in facial feminization surgery, detailing various aspects of the field but reporting no new clinical results; the authors highlight ongoing innovations and challenges.

Hirsute women with ovarian-sourced hirsutism are more likely to have irregular periods, with higher BMI and altered hormone ratios.

This study reports that familial frontal fibrosing alopecia was diagnosed earlier in premenopausal women compared to postmenopausal women, though long-term outcomes remain uncertain without a definitive treatment.

This study observed that in an ex vivo setting, 17β-estradiol increased CB1 expression in human hair follicles, suggesting possible sensitivity to endocannabinoids and a potential mechanism for hair therapy.

This review discusses the potential role of steroid 5α-reductase inhibitors in treating neuropsychiatric disorders related to dopaminergic hyperreactivity but reports no new clinical results.

This article introduces a new grading system called the FPHL Severity Index to better identify and monitor early stages of female pattern hair loss using clinical criteria.

This study provided the crystal structure of the human steroid 5α-reductase 2 enzyme and identified key molecular mechanisms for testosterone reduction and finasteride inhibition, aiding in understanding disease-causing mutations and potentially facilitating new drug development.