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This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.

This study provided a dynamic 4D atlas showing the development process of mouse hair follicles through a telescope-like model, revealing new insights into the origin of hair follicle stem cells.

In this study, researchers developed a multilayered gel bead culture model using a microgel-spotting device, successfully mimicking the early development of skin appendages and supporting in vitro hair follicle regeneration with structures resembling native hair follicles.

This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.

This study found that human hair follicle dermal papilla cells and keratinocytes self-assembled differently in 3D spheroid co-cultures, providing insights into cell distribution and organogenesis during skin regeneration.

In this study using Xenopus laevis embryos, reduced levels of the desmosomal protein desmoplakin led to defects in epidermal and cardiac structures, suggesting its crucial role in tissue integrity.

This study identified the presence of recognizable organelles, such as lysosomes and mitochondria, in both the keratinized fiber and the hardened inner root sheath of the Romney wool follicle.

This study used atomic force microscopy to image surface structures of human epidermal melanocytes, hair follicle amelanotic melanocytes, and mouse melanoma cells, revealing differences in branch structure and granule distribution.

This chapter reports an organ culture method that permits mouse embryonic skin tissues to develop similarly to in vivo conditions, revealing that epidermal growth factor inhibits hair follicle formation.

This study demonstrated that plucked human hair follicles cultured in a collagen gel matrix developed spike-like structures, suggesting a useful method to study outer root sheath cell growth and differentiation in vitro.

In this study, researchers found that hair follicle-like structures can be generated from collagen/chitosan porous scaffolds implanted with mouse hair follicle cells in vitro.

This study suggests that varying intersheet interactions may explain the differences between the two polymorphic forms of macrofibril assembly in Merino wool and hair.

In this study, researchers engineered ventral skin organoids (vSkOs) with specific cellular compositions and signaling environments to generate human amnion-like tissues called Amnioids, offering new tools for studying human development and potential regenerative therapies.

This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.

Skin organoids can regenerate hair by forming specific cell units with certain signals.

This study found that the weak tensile strength of pili torti hair may result from loose keratin intermediate filaments due to abnormalities in disulfide bonds.

This study found that Foxn1-like genes in fish and mice are functionally equivalent in activating hair keratin genes, whereas changes in the cephalochordate Foxn1-like gene result in inactivity.

This study discovered previously unknown structures in human hair shafts that may stabilize hair structurally and physicochemically.

This study found that Fibroblast growth factor-9 (FGF-9) accelerates epithelial invagination in engineered ectodermal organs and suggests its potential role in organogenesis and regeneration research.

This article discusses various skin pattern formations, their molecular mechanisms, and highlights the need for further understanding to connect molecular biology with organism phenotypes, without providing new clinical findings.

This study examined the unique structural features of sinus hair follicles in the shrew Sorex unguiculatus, which suggest a specialization for vibration sensing.

This review discusses three aspects of cell fate specification across Metazoa and reports no new experimental results, highlighting the formation of nematode equivalence groups, evolution of echinoderm skeletogenic mesoderm, and adult cell fate regulation.

This study describes a system for generating hair follicles from dissociated cells in mice, suggesting that successful development requires a foundational epithelial platform.

This review discusses spatial and temporal patterns in animals, focusing on skin appendage organs, but provides no new research findings.

This study developed immortalized cell-based models to screen and evaluate potential hair-care materials by forming hair follicle-like structures that respond to hair growth-promoting compounds.

This study found that hyaluronic acid increased the size and cell proliferation of mixed aggregates in a 3D culture model, indicating its role in human hair follicle germ-like structure formation without enhancing dermal papilla cell markers.

This case study reports a peculiar variant of an epidermal cyst in a patient, featuring unique characteristics like brownish, lumpy contents resembling bone marrow.

This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.

This study reports that eccrine sweat glands in mice predominantly develop on the footpads, offering a reference for skin research involving genetically engineered mice.