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The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.

Germ-free rats need biotin for growth and have different vitamin metabolism compared to regular rats.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.

Hair cortisol may be a good indicator of recent mood in people with bipolar disorder.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Androgens can cause hair growth in some areas and hair loss on the scalp.

"Male-pattern" hair loss is common in women, especially after menopause, and doesn't always mean there's a problem with hormone balance.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Both mouse and rat models are effective for testing alopecia areata treatments.

Genetics and hormones cause hair loss; finasteride treats it safely.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.