This study found that both levetiracetam and valproate sodium effectively reduced seizure frequency and duration in patients with refractory epilepsy, but levetiracetam had fewer side effects related to liver enzyme changes.
October 2010 in “Epilepsy Currents” This study found that inhibitory neurosteroids synthesized within glial cells can reduce seizure frequency in epileptic animals by enhancing inhibitory transmission via γ-aminobutyric acid receptors.
In this study, pruritus was the most frequent skin disorder observed in hemodialyzed patients, particularly among those undergoing long-term dialysis.
This study found that scalp melanoma in areas with androgenetic alopecia presents with more frequent detrimental mutations and may have a poorer prognosis due to late diagnosis linked to hair concealment.
9 citations
,
August 2023 in “Molecules” This study found that the peptides RMYYY and VMYMI displayed stronger binding energy and more frequent interactions with HPGDS compared to the native inhibitor, suggesting potential as future therapeutic drugs.
December 2025 in “Çukurova medical journal (Online)/Çukurova medical journal” In this retrospective review, increased frequencies of certain HLA-DRB1 alleles and low vitamin D3 levels were observed in men with androgenetic alopecia, suggesting an association with immunogenetic factors and potential relevance for screening and treatment decisions.
18 citations
,
January 2011 in “International journal of trichology” This case report describes a 9-year-old girl with pseudonits and highlights frequent challenges in correctly diagnosing this condition.
1 citations
,
October 2008 in “Expert Review of Dermatology” This review discusses frontal fibrosing alopecia, noting its frequent misdiagnosis and highlighting the need for larger studies to better understand its epidemiology, causes, and treatment options; it reports no new clinical findings.
January 2026 in “Journal of Dermatological Treatment” The researchers reported that oral finasteride 1 mg was associated with more frequent reports of sexual adverse events than dutasteride 0.5 mg, particularly after 2012, which may be influenced by the nocebo effect.
April 2023 in “World Journal of Advanced Research and Reviews” This case report describes common thyroid disorders in a β-thalassemia patient with frequent blood transfusions, emphasizing the need for monitoring thyroid function in such patients.
This study observed that patients with androgenetic alopecia had higher alexithymia scores and more frequent anxiety compared to control subjects, although no conclusive link to depression was found.
April 2018 in “Asian-Australasian journal of bioscience and biotechnology” This study conducted at Madras Veterinary College found that tick infestation was the most frequent diagnosis among hospitalized dogs with dermatological issues, with ectoparasiticides prescribed in 73% of cases.
56 citations
,
March 2010 in “Journal of Dermatology” This review provides a synopsis of 53 cases of temporal triangular alopecia, noting its frequent detection in early childhood and potential association with congenital diseases, but it reports no new clinical findings.
45 citations
,
February 2012 Among obese women potentially eligible for combined oral contraceptives, this study observed a higher frequency of non-alcoholic fatty liver disease in those with polycystic ovary syndrome.
32 citations
,
October 2015 in “Frontiers in Cellular Neuroscience” This study found that in male rat hippocampal slices, DHT is necessary for low frequency stimulation-induced long-term depression, while E2 synthesis is essential for high frequency stimulation-induced long-term potentiation.
30 citations
,
August 2016 in “Advances in radiation oncology” This study developed a mouse model for radiation cystitis that mimics human pathology and found that radiation exposure leads to increased urinary frequency and long-term weakening of urothelial integrity.
28 citations
,
April 2009 in “Annals of laboratory medicine” This study found that the DFS pattern occurs in about 28% of ANA-positive cases and is relatively frequent in autoimmune diseases, contrary to previous observations suggesting no link with these diseases.
27 citations
,
August 2015 in “Experimental Dermatology” In this study, electrical stimuli at low voltage and frequency settings promoted hair growth in vitro and in rabbit models, possibly by activating pathways like Wnt/β-catenin.
24 citations
,
January 2007 in “The FASEB Journal” This study developed a rat model for catamenial epilepsy, suggesting that neurosteroid withdrawal may increase seizure frequency and help test new treatments.
22 citations
,
February 2023 in “European Journal of Neurology” This study found that fremanezumab was effective in reducing migraine headache days by at least 50% for the majority of patients with high-frequency episodic or chronic migraine who had failed previous treatments.
22 citations
,
October 2012 in “Journal of Investigative Dermatology” This study found that C57BL/6 mice with a diet containing specific levels of vitamin A showed alterations in retinoid metabolism and increased frequency of cicatricial alopecias, suggesting dietary factors may play a role in this condition.
19 citations
,
February 2016 in “Journal of Biological Chemistry” In this study, researchers observed that knocking out KCNQ3 in mice increased firing frequencies in response to stimuli, particularly at slow mechanical indentation velocities, indicating a role in mechanosensory neuron sensitivity.
17 citations
,
November 2017 in “Experimental physiology” This study found that in newborn rats, progesterone's effects on apnoea frequency are influenced by a sex-specific balance between its metabolite allopregnanolone and progesterone receptors.
17 citations
,
October 2015 in “The Journal of Physiology” This study found that in newborn rats treated with caffeine, progesterone increased apnoea frequency by inhibiting breathing, suggesting it may not be suitable for preterm neonates without addressing allopregnanolone's effects.
12 citations
,
February 2023 in “Journal of Personalized Medicine” This review discusses the complex interplay of genetic and environmental factors in Type 1 Diabetes Mellitus and its frequent association with other autoimmune conditions, focusing on personalized medicine to potentially improve patient care.
11 citations
,
July 2014 in “Journal of The Royal Society Interface” This study demonstrates that modeling clone size independently of time offers analytical advantages for understanding cell distribution and mutation frequency in epithelial progenitors, extending applications beyond neutral models.
6 citations
,
November 2018 in “Dermatologic Therapy” This study suggests that the high prevalence of frontal alopecia in Chinese women may be linked to frequent ponytail styling, which could indicate traction alopecia.
5 citations
,
September 2023 in “Archives of Dermatological Research” In this retrospective study of 123 pediatric alopecia areata patients, hair loss episodes were most frequent in winter and showed significant correlations with air pressure and hours of sunlight, especially in non-atopic individuals, suggesting a role for climate factors in seasonal hair loss patterns.
5 citations
,
July 2020 in “Experimental Physiology” This study found that the dynamic characteristics of both cerebrovascular carbon dioxide reactivity and central respiratory chemoreflex decrease in the high frequency range and are not modified by exercise.
3 citations
,
November 2009 in “BMC dermatology” This study found that dermatologists in the southeastern U.S. often offer less frequent treatment for children with alopecia areata compared to adults, with more treatment also recommended for more advanced stages of hair loss.