99 citations,
August 2009 in “Nature Genetics” Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
91 citations,
August 2015 in “Anais Brasileiros De Dermatologia” Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.
65 citations,
September 2010 in “Journal of the Neurological Sciences” Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
64 citations,
June 2014 in “Journal of The American Academy of Dermatology” Researchers found a white halo around hair in most patients with a specific type of hair loss, which helps in early diagnosis and treatment.
64 citations,
July 1997 in “Journal of The American Academy of Dermatology” Finding eosinophils near hair bulbs helps diagnose alopecia areata.
61 citations,
February 2001 in “American Journal of Obstetrics and Gynecology” Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.
59 citations,
September 2008 in “Mycoses” Seborrheic dermatitis lowers quality of life more for women, younger people, and those with more education.
58 citations,
September 2012 in “Dermatologic Clinics” Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
58 citations,
April 2009 in “Dermatologic Surgery” Most women have a widow's peak and specific hairline features useful for designing hair restoration surgery.
54 citations,
May 1998 in “Urology” Men with enlarged prostates often have more severe baldness.
53 citations,
September 2011 Other common signs, not just the well-known immune cells around hair bulbs, are important for diagnosing hair loss from alopecia areata.
52 citations,
December 2000 in “Archives of Dermatological Research” Scalp skin barrier affects hair loss; personalized treatments needed.
49 citations,
May 2018 in “Endocrine” Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.
49 citations,
November 1992 in “Archives of dermatology” Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.
48 citations,
September 2013 in “Oncologist” Endocrine therapies for cancer significantly increase the risk of hair loss.
48 citations,
October 1996 in “Dermatologic clinics” Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.
46 citations,
May 2018 in “Dermatologic Surgery” PRP injections effectively treat hair loss, with positive results in both monthly and every three months treatments.
45 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” Using sharp tools and the right techniques in hair transplant surgery leads to less damage to hair follicles.
43 citations,
November 2019 in “American Journal of Clinical Dermatology” FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.
42 citations,
February 2016 in “Science” The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.
40 citations,
December 2004 in “Dermatology” Kenogen increases with hair loss in women.
37 citations,
June 2011 in “Journal of The American Academy of Dermatology” Loss of sebaceous glands and inflammation may contribute to the development of scarring alopecia.
37 citations,
January 1997 in “Clinics in Dermatology” Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.
35 citations,
November 2010 in “Journal of Cutaneous Pathology” Dilated follicular infundibula and increased catagen/telogen follicles are key indicators for diagnosing alopecia areata.
34 citations,
June 2010 in “Archives of Disease in Childhood” Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.
34 citations,
June 2007 in “The Journal of Dermatology” Most Korean systemic lupus erythematosus patients experienced hair loss, often as non-scarring diffuse hair loss, with non-scarring patch alopecia also common.
33 citations,
January 2013 in “Dermatology” Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.
33 citations,
January 2011 in “Elsevier eBooks” Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
32 citations,
November 2018 in “Anais Brasileiros de Dermatologia” In Brazil in 2018, the most common skin issues were acne, photoaging, and nonmelanoma skin cancer, with treatments often including topical medications and sunscreen.
31 citations,
January 2010 in “GenomeBiology.com (London. Print)” The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.