50 citations,
January 2016 in “The Journal of Clinical Endocrinology and Metabolism” Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.
25 citations,
March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
March 2023 in “Scholars international journal of obstetrics and gynecology” PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.
23 citations,
January 2016 in “Journal of Nanjing Medical University” Overweight women with PCOS are more likely to have excess male hormones.
2 citations,
July 2012 in “Journal of Pediatric and Adolescent Gynecology” A 12-year-old girl with very high testosterone and insulin resistance improved with birth control pills, suggesting PCOS can cause high testosterone without tumors.
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
3 citations,
March 2019 in “Post Reproductive Health” Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.
14 citations,
January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
11 citations,
October 2018 in “Hormone and Metabolic Research” Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
53 citations,
December 2015 in “JAMA Dermatology” Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.
10 citations,
April 2018 in “Maturitas” Excess male hormones in postmenopausal women can cause health issues and increase the risk of heart disease and diabetes; treatment depends on the cause.
11 citations,
November 2017 in “Electronic physician” Depression severity is not linked to PCOS markers like BMI, insulin resistance, or testosterone levels.
December 2015 in “JAMA Dermatology” Dermatologists can help diagnose endocrine disorders like PCOS and metabolic syndrome by looking at skin symptoms.
20 citations,
January 2003 in “Treatments in Endocrinology” Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
2 citations,
September 2008 in “Fertility and Sterility” Women with PCOS and higher BMI, especially those with morbid obesity, are at greater risk for depression.
The case showed the need for quick investigation of virilization in women and how emotional health is linked to physical health.
10 citations,
April 2006 in “Seminars in Reproductive Medicine” Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
October 2023 in “Journal of the Endocrine Society” Losing weight and taking birth control pills can greatly improve severe male hormone excess in women with PCOS.
75 citations,
June 1999 in “Pediatric Clinics of North America” The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
3 citations,
January 1992 in “Gynecological Endocrinology” 3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.
September 2012 in “African Journal of Urology” Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.
3 citations,
January 2018 in “Postępy Dermatologii i Alergologii” Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.
61 citations,
January 2015 in “Hormones” Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.
66 citations,
March 1998 in “Mayo Clinic Proceedings” Removing a testosterone-producing tumor cured a woman's sleep apnea and other symptoms.
October 2024 in “Journal of the Endocrine Society” Ovarian stromal hyperplasia can cause high testosterone in postmenopausal women and is treated by removing the ovaries.
46 citations,
January 2008 in “Climacteric” Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
October 2024 in “Journal of the Endocrine Society” Rare ovarian tumors can cause hyperandrogenism, even if imaging appears normal.
October 2024 in “Journal of the Endocrine Society” Leydig cell tumors can cause high testosterone and symptoms like hair loss in postmenopausal women, but surgery can improve these symptoms.
93 citations,
June 2001 in “The Journal of Clinical Endocrinology and Metabolism” Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.
28 citations,
October 1998 in “Baillière's clinical endocrinology and metabolism” Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.