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Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.

Different hair fiber development might explain why hair loss severity varies in patients with a specific genetic mutation, and treatments that thicken hair could help.

Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.

The document concludes that a high-protein, low-carb diet can lead to significant weight loss but requires caution and further research.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

Finding functions for unknown GPCRs is hard but key for making new drugs.

People distressed by minor skin changes should consult dermatologists with cosmetic expertise, and a public Cosmetic Dermatology Service with mental health support is recommended.

Herbal hair oils with Coconut, Curry leaves, Amla, Fenugreek, and Onion promote hair growth and are safe.

Some blood-thinning medications can increase the risk of bleeding, and certain factors like genetics and other health conditions affect their safety and effectiveness.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.