October 2010 in “eCommons (Cornell University)” This study found that mouse hair follicle stem cells use symmetric cell division for maintenance and fate determination, and identified Gata6 as a crucial factor for their differentiation.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers mapped gene expression in developing hair follicles to reveal unknown cell populations and markers, suggesting early establishment of cell fates in hair placodes.
3 citations
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September 2016 in “Hair transplant forum international” This abstract discusses the growing popularity of follicular unit extraction in hair restoration surgery but offers no clinical findings.
78 citations
,
August 2002 in “Experimental Dermatology” This study describes a simplified method for isolating and cultivating human hair follicle papillae that can be easily executed by new lab personnel.
16 citations
,
November 2020 in “In Vitro Cellular & Developmental Biology - Animal” This study explored the use of "microfollicles," a human hair follicle organoid model, as an in vitro tool for testing hair-growth substances, finding up to 75% overlap in gene expression changes with human clinical biopsy responses to minoxidil, indicating its potential for pre-clinical substance testing.
August 2003 in “Special report” This report introduces Barcelona - TrichoScan as a novel software tool purported to effectively analyze hair growth in patients with androgenetic alopecia or androgenetic effluvium, but it provides no clinical data.
January 2024 in “Updates in clinical dermatology”
November 2014 in “ACTUALIDAD MEDICA” This article discusses the potential of using ultrasonography to assess hair and follicular pathology non-invasively and reports no new clinical results.
April 2016 in “Journal of Investigative Dermatology” This study found that a newly developed peptide, FOL-005, significantly inhibited hair growth and counteracted minoxidil's effects in organ-cultured human male scalp skin and mouse models, without apparent toxicity.
2 citations
,
February 2024 in “STAR Protocols” In this research, an optimized protocol was developed for dissociating human scalp tissue to produce high-quality single-cell suspensions suitable for single-cell RNA sequencing, aimed at studying the transcriptomics of human hair follicles.
71 citations
,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents a novel in vitro assay using human folliculoid microspheres to research hair growth, which may facilitate preclinical testing of hair growth-modulatory agents.
The ProScope HR is an effective, user-friendly, and affordable tool for diagnosing hair loss.
3 citations
,
June 2021 in “Actas Dermo-Sifiliográficas” This study found that dermoscopy can identify typical features of Malassezia folliculitis, such as folliculocentricity and perilesional erythema, offering a valuable tool for diagnosing this condition in clinical settings.
September 2019 in “Journal of Investigative Dermatology” Sox13 is a new marker for early hair follicle development and differentiation.
29 citations
,
September 1997 in “PubMed” This paper reviews follicular hair transplantation techniques and planning, emphasizing careful evaluation and long-term strategy for achieving excellent cosmetic results.
80 citations
,
May 2011 in “Nature Cell Biology” This review discusses the progress in identifying stem cells responsible for tissue regeneration and highlights technological advances in tracking their behavior, but reports no new clinical results.
54 citations
,
October 2002 in “Journal of controlled release” This study found that increasing a drug's lipophilicity and adding ethanol to the donor phase can enhance its delivery to the hair follicle, although the precise transport mechanism remains unclear.
10 citations
,
January 2011 in “Journal of biomedical optics” This study found that optical coherence tomography provides highly reproducible and less variable measurements of hair shaft thickness compared to standard light microscopy, offering a promising noninvasive tool for clinical practice.
January 2024 in “Updates in clinical dermatology”
This research explores the use of serial block-face scanning electron microscopy to model the complex architecture of sheep wool fibres, focusing on the role and distribution of para- and ortho-cortical cells in determining wool curliness, though the mechanism remains unclear.
69 citations
,
January 2015 in “Current problems in dermatology” This review discusses trichoscopy as a noninvasive, effective technique for diagnosing various hair loss conditions and monitoring treatment, highlighting its potential to reduce scalp biopsy necessity.
3 citations
,
January 2014 in “Archives of Aesthetic Plastic Surgery” This study found that using a combination of video microscope for slivering and loupe magnification for graft-cutting in hair transplants achieved nearly double the graft productivity with similar transection rates compared to using only a digital video microscope.
October 2015 in “CRC Press eBooks” This article reviews the use of trichoscopy for diagnosing and monitoring various scalp conditions, but it presents no new experimental findings; the authors emphasize its precision in noninvasive evaluation.
This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.
13 citations
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April 2016 in “Journal of Visualized Experiments” This study describes a method for isolating stem cells and keratinocytes from mouse hair follicles using FACS technology, facilitating the study of stem cell biology.
January 2011 in “Zhongguo nongye Kexue” This study successfully established a transgenic sheep fibroblast cell line expressing the spider dragline silk protein gene, laying groundwork for developing transgenic sheep with this capability in hair follicles.
February 2020 in “International Journal of Current Microbiology and Applied Sciences” This study found that canine hair follicle stem cells in vitro expressed markers associated with multipotency, suggesting their potential role in the hair cycle.
212 citations
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September 2015 in “Journal of Investigative Dermatology” This article presents a comprehensive guide for classifying human hair follicle cycle stages in vivo using scalp xenografts on immunocompromised mice, offering valuable resources for researchers in the field.
19 citations
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May 2016 in “Cytotechnology”