19 citations
,
February 2013 in “The American Journal of Dermatopathology” This study found that follicular density and various hair growth ratios differ statistically between nonscarring and scarring alopecia, though significant overlap exists due to factors like sample size and scalp variation.
18 citations
,
January 2017 in “Annals of dermatology/Annals of Dermatology” This study found that Th17 lymphocytes may play a more crucial role than cytotoxic T cells in the development of alopecia areata due to their infiltration around the hair bulb/bulge, which exacerbates hair loss as histopathological grade worsens.
18 citations
,
October 2002 in “Veterinary dermatology” This study observed that follicular dysplasia in Weimar Pointers produces histopathological features and hair abnormalities similar to color dilution alopecia, though less severe.
17 citations
,
May 2015 in “Aesthetic Plastic Surgery” FUE hair transplantation using a micromotor is effective and gives natural results with few complications.
17 citations
,
June 2011 in “Dermatologic Surgery” This abstract provides no results; it contains subscription and journal information and does not discuss any study or findings.
17 citations
,
January 2010 in “PubMed” This review explores factors affecting graft growth and survival in hair restoration, emphasizing the importance of fundamental care practices while considering advanced storage solutions and additives, but reports no new findings.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article discusses follicular cell implantation as a potential solution for hair restoration limitations, but notes inconsistencies and challenges in human applications, reporting no new clinical results.
14 citations
,
July 2016 in “Anatomical Science International” This study revealed that in androgenic alopecia, the proximal attachment of the arrector pili muscle to the hair follicle is often lost or significantly reduced.
13 citations
,
August 2002 in “Dermatologic Surgery” This paper introduces Follicular Unit Extraction and reports the FOX Test can identify suitable candidates, with about 25% of patients being ideal and 35% being good candidates for the procedure.
11 citations
,
April 2016 in “Dermatologic Surgery” This study concluded that to accurately calculate the transection rate in follicular unit extraction, it's essential to account for both extracted and hidden transections, which differ based on surgeon expertise.
11 citations
,
August 2017 in “American Journal of Dermatopathology” This study found that the Elastic Verhoeff–Van Gieson stain may help differentiate between follicular streamers and scars in cicatricial and noncicatricial alopecias by highlighting differences in the elastic fiber network on horizontal scalp biopsy sections.
9 citations
,
May 2020 in “Journal of Cosmetic Dermatology” This review discusses various follicular unit excision methods, punch designs, and motorized devices, highlighting their roles in reducing hair follicle transection rates and optimizing graft harvesting for individual patient characteristics.
9 citations
,
March 2020 in “Dermatologic Surgery” This study found that both FUE and FUT methods are equally effective in producing high-quality hair grafts, with FUE offering the advantage of less noticeable scarring compared to FUT.
9 citations
,
September 2016 in “Plastic and reconstructive surgery. Global open” In this study, a curved nonrotary punch was found to achieve the lowest follicular unit transection rates of less than 5% compared to conventional rotary punches in hair transplantation for patients with tightly curled Afro-textured hair.
9 citations
,
January 2015 in “Current problems in dermatology” This review discusses partial longitudinal-follicular unit transplantation (PL-FUT) for hair loss and notes its potential to multiply hair follicles while preserving donor areas, but reports no new clinical results.
8 citations
,
February 2016 in “The American Journal of Dermatopathology” In this study, the researchers found that transplanted hair follicles undergo significant morphological changes, including a thickened dermal sheath and increased hair shaft diameter, which are associated with altered follicular vascularization.
8 citations
,
September 2002 in “Genes to Cells” This study suggests that label-retaining cells in the hair follicle contribute to follicular renewal, indicating a specific role in the hair cycle by proliferating during the late telogen phase.
8 citations
,
April 2019 in “Dermatologic Therapy” This study found that applying topical tretinoin can influence follicular sulfotransferase expression, enabling 43% of predicted nonresponders to minoxidil to respond positively in the context of androgenetic alopecia.
5 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” This study found that the trichogenicity of cultured human outer root sheath follicular keratinocytes decreased with longer cultivation periods and was significantly influenced by the expression of the transcription factor FOXA2.
4 citations
,
January 2005 in “Elsevier eBooks” This article discusses the key considerations and techniques necessary for successful Follicular Unit Transplantation in hair restoration surgery and reports no new clinical results.
3 citations
,
July 2011 in “Folia Histochemica et Cytobiologica” This study concluded that the inner root sheath inhibits the expression of certain differentiation markers in hair bulbs, with calcium-induced changes paralleling those seen in hair follicle mid-segments.
3 citations
,
June 2005 in “Ophthalmology Clinics of North America” Follicular unit transplantation treats hair loss and restores eyebrows with short recovery and natural results.
2 citations
,
March 2020 in “Medical journal, Armed Forces India” This study found that hair transplantation using the follicular unit extraction method significantly improved hair density and patient satisfaction in males with androgenetic alopecia, especially those younger than 33 and with less severe hair loss.
2 citations
,
January 2020 in “American Journal of Clinical Research and Reviews” This study suggests that hair follicles may be the primary target in the onset of various skin diseases, potentially spreading to affect the surrounding epidermis.
2 citations
,
September 2002 in “Dermatologic Surgery” This study describes how arrector pili muscles form a single muscular structure shared by all hair follicles within a follicular unit at the isthmus level in scalp skin.
1 citations
,
November 2024 in “Pharmaceutical Sciences” This review study found that vesicular carriers like liposomes, niosomes, invasomes, and transferosomes can enhance drug penetration through follicles, benefiting treatments for alopecia, acne, and infections, as well as potentially facilitating systemic delivery of antihypertensive drugs and insulin.
1 citations
,
September 2016 in “Indian Journal of Plastic Surgery” This article describes a modified follicular unit extraction technique using a reverse rake scalp elevator, which may reduce follicular transection rates in hair transplantation from the lower occipital donor region.
1 citations
,
June 2017 in “Actas Dermo-Sifiliográficas” This review discusses the follicular unit extraction technique for hair transplantation, noting its rise in popularity due to patient demand and improved surgical skills, but reports no new clinical results.
May 2026 in “International Journal of Drug Delivery Technology” This study found that infiltrating dilute adrenaline into the recipient area during implanter-based FUE hair transplantation significantly reduced intraoperative bleeding, improving graft precision and visualization, without major safety concerns among the 50 patients observed.
May 2026 in “International Journal of Drug Delivery Technology” This clinical trial found that using a 45-degree angled implanter with the bevel facing the skin in FUE hair transplantation significantly reduced insertion resistance, graft popping, and bleeding, while improving efficiency and graft alignment compared to conventional methods.