Follicular Unit Extraction for Hair Transplantation: An Update

    June 2017 in “ Actas Dermo-Sifiliográficas
    F. Jiménez‐Acosta, I. Ponce-Rodríguez
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    TLDR Follicular Unit Extraction (FUE) is a hair transplant method with less scarring and discomfort but requires skilled surgeons and has limitations on graft numbers per session.
    The 2017 document reviews Follicular Unit Extraction (FUE), a hair transplant technique that extracts follicular units using small punches, offering advantages like minimal scarring and less discomfort compared to Follicular Unit Transplantation (FUT). FUE is labor-intensive, time-consuming, and requires significant skill from surgeons, who can use manual, motorized, or robotic systems. It also allows for hair extraction from body areas other than the scalp. However, FUE has limitations, such as a recommended maximum of 3000 to 4000 follicular units per session to prevent a moth-eaten look and potential concerns about graft growth compared to FUT. The document emphasizes the importance of surgeon training and suggests proficiency in both FUE and FUT to provide the best patient care.
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      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

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      The conversation is about the progress of verteporfin in hair loss trials, with users expressing curiosity about its effectiveness and updates. Specific treatments mentioned include FUE (Follicular Unit Extraction) combined with verteporfin, with one reported case of donor area regrowth after a year, and three patients being monitored post-treatment by Dr. Bloxham with monthly updates on YouTube.

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