May 2022 in “Portuguese Journal of Dermatology and Venereology” In this study, a case of chronic skin ulcer due to livedoid vasculopathy fully healed following hair-follicle transplantation, suggesting potential effectiveness of this treatment approach.
This study reported that autogenic hair follicle transplantation provided good cosmetic results and improved quality of life for patients with post-irradiation alopecia, despite delayed hair regrowth due to blood supply deficits.
November 2023 in “International Journal of Medical Sciences” This review examines the mechanisms of hair follicle development and regeneration, discussing current hair loss treatments and emerging therapies like low-level laser therapy and stem cell therapy, which the authors suggest show promise in managing hair loss.
November 2022 in “Regenerative Therapy” This review discusses various tissue engineering approaches for hair follicle regeneration and biomaterials used, emphasizing its potential despite current clinical challenges.
January 2017 in “Springer eBooks” This review discusses recent advancements in hair follicle regeneration technologies, including the authors' own development of functional hair regeneration through bioengineered follicle germ transplantation, but reports no new clinical results.
208 citations
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December 2003 in “Journal of Investigative Dermatology” This study found that dermal papilla and peribulbar dermal sheath cup cells in mice can both induce hair follicle formation, suggesting they may have similar functional roles in hair growth.
February 2026 in “Biochemical and Biophysical Research Communications” This study identifies a specific cell population, PDGFRα+/Sca1+/CD34+ mesenchymal cells, which play a crucial role in regenerating hair follicles by promoting the downgrowth phase of the hair cycle, offering insights into organ morphogenesis and stem cell niches essential for adult hair regeneration.
77 citations
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April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
51 citations
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November 2010 in “Dermatologic Surgery” This study measured the lengths and depths of different portions of occipital scalp hair follicles and suggested cutting below 1 mm for hair regeneration procedures to avoid damaging the bulge zone.
33 citations
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September 1998 in “Dermatologic Surgery” This article proposes a classification for small graft transplants that includes technical factors to improve communication and facilitate comparative studies, reporting no new clinical results.
26 citations
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October 2012 in “Dermatologic Clinics” This article reviews recent advancements in hair transplantation techniques, particularly follicular unit transplantation, and suggests an expansion of its applications beyond male pattern hair loss, but reports no new results.
16 citations
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April 2009 in “Dermatologic Surgery” The place where hair is transplanted can change its growth rate and length but not its thickness.
15 citations
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May 2004 in “Facial Plastic Surgery Clinics of North America” This article discusses follicular cell implantation as a potential solution for hair restoration limitations, but notes inconsistencies and challenges in human applications, reporting no new clinical results.
13 citations
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October 2002 in “Journal of Investigative Dermatology” This study found that only one upper portion of a bisected human hair follicle successfully regenerated a complete new follicle with a pigmented hair in nude mice, although the overall success rate was very low.
11 citations
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January 2018 in “Annals of Dermatology” This case study reports that localized telogen effluvium may be a cause of hair loss following hair transplantation, based on observations in two patients with diffuse hair shedding primarily in the frontal and temporal scalp areas.
11 citations
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January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Hair transplant and applying 5% minoxidil solution can effectively treat permanent hair loss, but it may change hair direction in some cases.
9 citations
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July 2020 in “Biomedicine & Pharmacotherapy” This study found that Pep-1-mediated mitochondrial transplantation was as effective as PRP therapy in restoring hair loss related to aging in mice, with distinct improvements in hair and skin-related measures.
9 citations
,
March 2020 in “Dermatologic Surgery” This study found that both FUE and FUT methods are equally effective in producing high-quality hair grafts, with FUE offering the advantage of less noticeable scarring compared to FUT.
9 citations
,
January 2005 in “Journal of Cosmetic and Laser Therapy” This review discusses current concepts in hair transplantation, emphasizing the importance of patient consultation and alternative therapies like finasteride and minoxidil, but does not report new experimental findings.
8 citations
,
January 2015 in “Experimental Dermatology” This commentary honors Shoji Okuda's pioneering but overlooked work on hair transplantation techniques from 1939, detailing comprehensive experiments that were rediscovered and translated into English decades later.
8 citations
,
January 2008 in “Journal of Cosmetic and Laser Therapy” This paper provides an overview of modern hair transplantation techniques and discusses the importance of patient selection and medication use for male pattern hair loss, but it reports no new results.
8 citations
,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” This review explains how modern hair transplantation techniques use smaller, natural hair follicle groupings to create a more natural appearance without reporting new clinical results.
7 citations
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September 2015 in “Actas Dermo-Sifiliográficas” This article reviews the challenges of treating frontal fibrosing alopecia and the potential role of hair transplantation, noting the lack of effective medical treatments and uncertainty surrounding transplant outcomes.
6 citations
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September 2020 in “Advanced Biology” This study found that using the OptoTrkA system to control TrkA activity with blue light enhanced proliferation, migration, and differentiation of hair-follicle-derived stem cells into neuronal and glial cells.
5 citations
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December 2016 in “Microscopy Research and Technique” This study suggests that prenatal infusion of epidermal neural crest stem cells may improve certain neural markers and reduce cortical injury in a mouse model of methylazoxymethanol-induced malformations.
5 citations
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September 1998 in “Atlas of the oral and maxillofacial surgery clinics of North America” Hair transplantation and micrografting, used for baldness, involve moving hair follicles from hair-rich to bald areas, requiring careful procedure and post-care for success.
4 citations
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June 2020 in “Journal of Cosmetic Dermatology” This review describes the edge out punch for follicular unit excision, which may reduce follicle transection with its thicker walls and internal bevel design compared to other punch shapes, but reports no new clinical results.
4 citations
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January 2016 in “Advances in experimental medicine and biology” This study established that cryopreservation methods can maintain the pluripotency and hair growth potential of hair follicle-associated pluripotent stem cells, enabling potential applications in regenerative medicine and hair transplantation.
4 citations
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May 2013 in “Annals of Plastic Surgery” In this case report, the authors found that hair transplantation on a free microvascular flap may be a viable and effective option for achieving good aesthetic outcomes when treating residual alopecia following reconstruction of large scalp defects.
4 citations
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February 2008 in “Dermatologic Surgery” Hair transplant surgery successfully restored a woman's pubic hair, improving her appearance and satisfaction.