August 2021 in “Acta Haematologica Polonica” This paper discusses the diagnostic challenges and treatment options for folliculotropic mycosis fungoides, emphasizing the differing prognoses between its indolent and aggressive subtypes and reporting no new clinical results.
January 2026 in “Dermatologic Therapy” This review discusses folliculotropic mycosis fungoides, highlighting its diagnostic criteria and therapeutic strategies based on disease staging, but does not report new clinical findings.
39 citations
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July 2015 in “British Journal of Dermatology” This article discusses the pseudo 'fringe sign' in frontal fibrosing alopecia, highlighting that it is not solely related to traction, and it reports no new clinical results.
1 citations
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March 2022 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that HIF-P4H-2 function in FoxD1-lineage cells is crucial for normal hair follicle development and homeostasis in mice, implicating disrupted HIF, TGF-β, and Notch signaling pathways in associated defects.
This case study documented a 36-year-old woman with postpartum-onset frontal fibrosing alopecia who showed significant improvement in hair regrowth after early combination therapy with dutasteride, tofacitinib, and intralesional triamcinolone acetonide, suggesting potential benefits of multimodal treatment in this typically irreversible condition.
May 2015 in “Journal of the American Academy of Dermatology” Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.
April 2018 in “Journal of Investigative Dermatology” This study found that Fgf20 signaling facilitates fibroblast migration and influences dermal condensate cell development during hair follicle morphogenesis by supporting cellular activities such as cell cycle exit and specific cell shape adoption.
May 2026 in “Organoid Research” This review discusses recent advancements in hair follicle organoid technology for alopecia treatment but presents no new experimental results, emphasizing the potential for clinical applications and drug screening.
April 2016 in “Expert opinion on orphan drugs” This review explores current therapeutic options for frontal fibrosing alopecia, noting the use of finasteride, topical tacrolimus, hydroxychloroquine, and excimer laser in managing the condition, but reports no new clinical results.
This study reported that prompt diagnosis and treatment with 5-alpha-reductase inhibitors and topical immunomodulators are key to mitigating the effects of frontal fibrosing alopecia and preventing permanent hair loss.
December 2025 in “International Journal of Molecular Sciences” In this study, O. forskahlii seed oil was found to promote hair growth in rats and exhibit anti-aging effects on human skin cells by enhancing fibroblast proliferation and inhibiting inflammation and enzyme activity, indicating potential for cosmetic use.
57 citations
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January 2003 in “Clinical and experimental dermatology” This study identified postmenopausal frontal fibrosing alopecia as a distinct form of scarring alopecia in postmenopausal women, noting a potential link with a history of bilateral oophorectomy.
9 citations
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January 2023 in “Journal of Clinical Medicine” This study presents a validated questionnaire, the FFA-QLI, which effectively assesses and differentiates the quality of life impact among patients with frontal fibrosing alopecia, showing greater sensitivity in identifying severe cases than the DLQI.
3 citations
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February 2022 in “Cureus” This study observed an alopecia syphilitica-like pattern of hair loss in a woman with frontal fibrosing alopecia, suggesting it may be another atypical presentation of the condition.
December 2016 in “Journal of Dermatology and Dermatologic Surgery” In this study, the Instant Follicular Hair Unit Transplant technique demonstrated superior hair growth compared to conventional FUE in patients with androgenetic alopecia, although it requires a steeper learning curve for surgeons.
1 citations
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May 2014 in “European Journal of Inflammation” This study found that a topical lotion containing minoxidil, hydrocortisone butyrate, and 17α-estradiol improved or stabilized frontal fibrosing alopecia in 35 out of 40 women over 36 months.
32 citations
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July 2017 in “Oncotarget” This study found that intermittent treatment with FTI lonafarnib and sulforaphane may be a promising therapeutic approach for children with Hutchinson-Gilford progeria syndrome, as it improved the cellular phenotype.
March 2024 in “Biochimica et biophysica acta. Molecular basis of disease” This study found that deferoxamine may protect against sensorineural hearing loss by reducing oxidative stress-induced hair cell death through iron chelation and activation of the Nrf2 signaling pathway in lab models.
33 citations
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January 2010 in “Case reports in dermatology” This article presents a case study of a 50-year-old woman with frontal fibrosing alopecia and discusses the role of dermoscopy in differentiating it from other types of alopecia, reporting no new clinical results.
1 citations
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October 2023 in “The Laryngoscope” In this study, single-port endoscopic removal of forehead osteoma in adult patients showed complete tumor removal with excellent cosmetic results, highlighting otolaryngologists' expertise in minimally invasive techniques and achieving low surgical morbidity.
40 citations
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January 2013 in “International journal of trichology” This study found that among women with frontal fibrosing alopecia, 100% showed dermoscopic elements suggestive of the condition, with perifollicular erythema often indicating disease activity.
9 citations
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August 2014 in “Journal of The American Academy of Dermatology” This article discusses the authors' concerns over the misinterpretation of studies linking smoking and frontal fibrosing alopecia, clarifying that neither study suggests smoking is protective against the condition.
1 citations
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August 2024 in “Anais Brasileiros de Dermatologia” This review discusses the non-follicular skin manifestations of frontal fibrosing alopecia and how they affect diagnosis and treatment, but reports no new clinical results.
134 citations
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June 2012 in “International Journal of Oral and Maxillofacial Surgery” This article discusses current methods in facial feminization surgery for transsexual women and reports no new clinical results, focusing instead on various surgical techniques used to feminize facial features.
1 citations
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May 2024 in “Skin Appendage Disorders” In this study, researchers analyzed trichoscopy findings in black patients with FFA to aid in precise diagnosis and treatment, highlighting the importance of understanding disease characteristics to improve hair care in this group.
February 2026 in “Indian Dermatology Online Journal” This study reports that oral tofacitinib treatment in a patient with refractory lichen planus pigmentosus and frontal fibrosing alopecia resulted in near-complete resolution of hyperpigmentation and cessation of hairline recession over 18 months, and suggests it may be a promising therapy for these challenging conditions.
8 citations
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September 2011 in “European Journal of Dermatology” This study reports that most cases of frontal fibrosing alopecia did not show significant improvement with available treatments, and effective management remains unproven.
July 2019 in “Medical Science and Discovery” This study retrospectively analyzed 14 postmenopausal women with frontal fibrosing alopecia, noting that 57% experienced total eyebrow loss, and all received various steroid treatments, highlighting the importance of early diagnosis to potentially delay disease progression.
August 2019 in “Journal of The American Academy of Dermatology” This study found that a bleach bath treatment with 0.005% HOCI reduced the expression of certain serine proteases in cultured keratinocytes and lowered skin pH in atopic dermatitis patients, potentially improving symptoms by modulating the NF-kB pathway.
June 2026 in “Annals of Medicine and Surgery” This study highlights the approval of orforglipron under the FDA's National Priority Voucher program, emphasizing its significance as a convenient oral treatment option with beneficial effects on glycemic and lipid profiles for diabetes and obesity management.