This study found that applying an ethanol extract of Prasiola japonica improved hair regrowth, length, and follicular density in testosterone-induced hair loss conditions in mice, while also promoting dermal papilla cell proliferation and reducing dihydrotestosterone production, though effects were less pronounced than those of minoxidil.
September 2016 in “Springer eBooks” This review discusses the application of mesenchymal stem cells and their secretory factors for skin and hair regeneration and reports no clinical results; the authors highlight the progress and call for practical applications.
February 1999 in “The anatomical record” This study observed defects in hair cuticle cross-linking in some, but not all, mouse mutants with sparse or structurally unsound hair.
75 citations
,
November 1965 in “Textile research journal” This study found that papain/bisulfite disintegrates human hair cuticles by dissolving the endocuticle, potentially accelerated by ethanol's removal of cell membrane material.
55 citations
,
August 2015 in “AAPS PharmSciTech” This study reports that a newly developed polyherbal phospholipid complex cream containing Citrus auranticum and Glycyrrhiza glabra extracts improved polyphenol retention in the skin, suggesting potential as an anti-aging cosmeceutical.
4 citations
,
May 2025 in “Stem Cell Research & Therapy” This review explores the potential of extracellular vesicle therapy as a novel strategy to delay intervertebral disc degeneration and enhance tissue repair, by modulating key pathogenic mechanisms, with a focus on the molecular components and bioengineering modifications of extracellular vesicles.
2 citations
,
March 2025 in “Industrial Crops and Products” This study found that peach kernel oil extracted via supercritical fluid extraction had higher quality and antioxidant properties than oil obtained by other methods, effectively protecting human hair follicle keratinocytes from oxidative damage.
1 citations
,
December 2022 in “Parasitologists United Journal” This study observed that M. domestica larva-derived chitosan and gut extracts enhanced wound healing and collagen deposition in both immunocompetent and immunosuppressed mice, indicating potential benefits for combined therapy.
This study suggests that a herbal shampoo made from plant ingredients may be a promising natural remedy for hair fall and dandruff, demonstrating good quality and safety.
140 citations
,
August 2011 in “Biomaterials” This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.
137 citations
,
January 2000 in “Skin Pharmacology and Physiology” This review outlines the factors affecting skin greasiness and sebum production, highlighting measurement challenges but reports no new clinical findings; further research may guide sebosuppressive treatments for acne.
118 citations
,
July 2005 in “Journal of Ethnopharmacology” In this study, the aqueous extract of Eclipta alba and its hydrolyzed fraction showed nootropic activity and reduced stress-induced alterations in rats.
111 citations
,
April 2023 in “Ultrasonics Sonochemistry” This review discusses the extraction, purification, and biological activities of maidenhairtree polysaccharides, emphasizing the higher efficiency of ultrasound-assisted extraction, but it reports no new clinical results.
69 citations
,
December 2011 in “Journal of Ethnopharmacology” This study found that Carthamus tinctorius exhibited the strongest 5α-reductase inhibitory and hair growth promoting activities among evaluated Thai herbs, suggesting potential for developing alternative hair loss treatments.
68 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” This study suggests that botanical 5AR inhibitors like Serenoa repens and β-sitosterol may improve symptoms of androgenetic alopecia, with 60% of treated subjects showing improvement compared to placebo.
41 citations
,
July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.
37 citations
,
January 1993 in “Yakugaku zasshi” This study found that a 70% ethanolic extract from Ginkgo biloba leaves promotes hair regrowth in C3H mice.
31 citations
,
November 2013 in “Dermatologic Clinics” This article discusses the use of a robotic system for hair graft harvesting in hair restoration surgery, focusing on its capabilities and the advantages and disadvantages, but it reports no new clinical findings.
30 citations
,
February 2018 in “Journal of Pharmacy and Pharmacology” This review discusses the traditional uses and pharmacological properties of Hedychium spicatum, noting that while some traditional uses are supported by scientific studies, further research on its applications is needed.
30 citations
,
October 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This article reviews modern hair transplantation techniques, noting that while many innovations have improved natural-looking results and expanded candidate eligibility, some may have hidden drawbacks, and it reports no new results.
28 citations
,
March 1942 in “Journal of Endocrinology” This article reviews studies on thyroid influence on hair growth, noting varied results, including accelerated growth in some normal and underfed rats after thyroid administration, but reports no clinical results.
27 citations
,
April 2011 in “International journal of legal medicine” This study reports that the completeness of DNA degradation in hair during cornification varies among individuals and affects the success rates of forensic hair DNA analysis.
26 citations
,
October 2012 in “Dermatologic Clinics” This article reviews recent advancements in hair transplantation techniques, particularly follicular unit transplantation, and suggests an expansion of its applications beyond male pattern hair loss, but reports no new results.
26 citations
,
November 2002 in “Planta medica” In this study, the methanol extract of Cercidiphyllum japonicum heartwood was found to stimulate the proliferation of mouse hair epithelial cells, with several isolated compounds showing significant proliferative activities.
23 citations
,
September 2014 in “Journal of The American Academy of Dermatology” This study reports that a robotic device effectively harvests hair follicles with a 95.1% yield in Korean patients undergoing hair restoration surgery.
18 citations
,
January 2007 in “Pharmaceutical Biology” This study found that petroleum ether extracts of Citrullus colocynthis reduced hair growth initiation time and advanced more hair follicles to the anagen phase in albino rats compared to untreated controls and minoxidil.
18 citations
,
April 2010 in “Actas Dermo-Sifiliográficas” This review discusses the current procedure for follicular unit hair transplantation, emphasizing its natural and reproducible results, but does not report new clinical findings.
17 citations
,
February 2013 in “PLOS ONE” This study found that 6-gingerol, a component of ginger, suppresses hair growth rather than promoting it, both in vitro and in vivo, suggesting potential use in hair removal treatments.
17 citations
,
January 2025 in “Journal of Nanobiotechnology” This review discusses the potential of bacterial extracellular vesicles in regenerative medicine, highlighting their advantages in addressing current EV challenges, and provides strategies for optimizing their preparation; it reports no new clinical results.
16 citations
,
January 1980 in “Planta Medica” This study found that alcoholic extracts of Cinchona succirubra, Dictamnus dasycarpus, Brassica juncea, and Sophora flavescens promoted hair growth in 5-week-old mice.