September 2025 in “Brazilian Journal of Health Review” This review highlights increased cases of alopecia frontal fibrosante among Black women, emphasizing the need for ethnically diverse research and culturally sensitive management practices, but reports no new clinical findings.
March 2025 in “Journal of Clinical Medicine” This review discusses the unique clinical features, challenges in diagnosis, and treatment protocols of frontal fibrosing alopecia in men, noting the overlap with other types of alopecia and the need for further studies.
February 2025 in “Actas Dermo-Sifiliográficas” This study found that oral minoxidil can improve hair and eyebrow growth and increase the density of the frontotemporal hairline in patients with FFA, though adverse effects were reported by a third of participants.
In this narrative review, researchers evaluated existing literature on the treatment of frontal fibrosing alopecia, finding that while no curative treatment exists, clinical improvements can be achieved through personalized and combined therapy approaches.
November 2024 in “International Journal of Women’s Dermatology” In this study of a Colombian sample, the researchers found that while sex, alopecia location, and symptoms aligned with global reports, age at presentation, tobacco use, and use of wigs and dyes were different from those noted in other countries.
November 2024 in “Actas Dermo-Sifiliográficas” In this retrospective study, oral minoxidil was found to improve the density of the frontotemporal hairline in 45.1% of patients with frontal fibrosing alopecia, with some also experiencing eyebrow and eyelash growth; however, adverse effects such as hypertrichosis were noted in 33.6% of the participants.
June 2024 in “BioSCIENCE” This study reviewed the use of microinfusion of microparticles (MMP®) with methotrexate for treating alopecia frontal fibrosante and found it reduced symptoms associated with the condition and improved specific scalp measurements, showing that the technique is safe and well-tolerated.
April 2024 in “Journal of clinical medicine” This review discusses various therapeutic options for frontal fibrosing alopecia and highlights the need for more research, as existing data are largely retrospective and lack precise treatment guidelines.
January 2024 in “Revista Dermatológica Centro Uraga” This report describes two male patients with frontal fibrosing alopecia, a lymphocytic scarring hair loss condition often seen in postmenopausal women, highlighting its occurrence in men and its manifestation around the frontal hairline and other body areas.
June 2023 in “Brazilian Journal of Case Reports” In this case report, a patient with early-stage Frontal Fibrosing Alopecia showed substantial improvement in follicular density and inflammation control after three monthly sessions of Botulinum Toxin Type A administered via microinfusion.
March 2023 in “Journal of clinical review & case reports” This study observed that in Mexico, Frontal Fibrosing Alopecia predominantly affects postmenopausal women, with an increased incidence in recent years, and highlights the challenge of early diagnosis to prevent irreversible hair loss.
March 2023 in “Revista médica Clínica Las Condes” This study observed a tendency for patients with frontal fibrosing alopecia to have more androgen receptors in their scalp than healthy controls, though this difference was not statistically significant.
This study found that home use of low-level light therapy reduced inflammation and symptoms like itching and burning in women with frontal fibrosing alopecia over six months.
This study found a significant discordance between clinical symptoms and dermatoscopic signs with histopathological inflammation in patients with LPP and AFF, affecting diagnostic and therapeutic approaches.
June 2022 in “Revista del Hospital Italiano de Buenos Aires” This case report describes a 58-year-old male patient with alopecia frontal fibrosante in areas also affected by vitiligo, highlighting a possible association with autoimmune disorders.
March 2022 in “Más dermatología” This report discusses the potential overlap between chronic cutaneous lupus and frontal fibrosing alopecia, noting ongoing debate over the significance of their association without presenting new clinical results.
February 2022 in “Brazilian Journal of Health Review” In this study, researchers found that among women with frontal fibrosing alopecia and hyperpigmented facial lesions, most cases were diagnosed with lichen planus pigmentosus, while some were identified as melasma or drug-induced.
January 2022 in “Investigative News in Education (Universidad de Costa Rica)” This study found that consensus was not reached among Costa Rican dermatologists on diagnosis and treatment criteria for lichen planopilaris and frontal fibrosing alopecia using the Delphi method.
September 2021 in “Revista Interdisciplinar em Saúde” In this observational study, treatment with oral isotretinoin was reported to stabilize hair loss in patients with frontal fibrosing alopecia, offering potential guidance for clinicians on its therapeutic use, with implications for improving affected patients' self-esteem.
September 2021 in “Revista interdisciplinar em saúde” This study reported that oral isotretinoin effectively stabilized frontal fibrosing alopecia in patients, which may help guide healthcare providers in managing this condition related to hair loss and self-esteem.
October 2020 in “International Journal of Research in Dermatology” This review discusses the possible immune-mediated and environmental factors contributing to frontal fibrosing alopecia but reports no new clinical findings, emphasizing the need for standardized treatment evaluations.
September 2020 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” This review discusses fibrosing alopecia in a pattern distribution, noting its trichoscopic and histopathological features, and emphasizes the importance for dermatologists to recognize and treat it early to prevent irreversible follicular damage.
January 2020 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” This study reports that frontal fibrosing alopecia in Brazilian patients is common in postmenopausal women and often associated with hypothyroidism and facial irritation from cosmetic products.
September 2019 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Isotretinoin at low doses effectively treats facial papules in frontal fibrosing alopecia.
July 2018 in “Elsevier eBooks” This review discusses the evolving understanding of frontal fibrosing alopecia as a generalized skin condition with diverse manifestations, and reports no new clinical results.
July 2018 in “Nasza Dermatologia Online” The authors report two clinical cases of scarring alopecia in a mother and daughter, suggesting a potential link between frontal fibrosing alopecia and ulerythema ophryogenes.
March 2018 in “Dermatología Argentina” This study found that postmenopausal women in Argentina with frontal fibrosing alopecia had a higher average age of diagnosis than previously reported, with similar clinical features to international cases.
September 2017 in “Journal of Dermatology & Cosmetology” This study reports a case of frontal fibrosing alopecia associated with hepatitis C treatment involving interferon and ribavirin.
December 2016 in “Anales del sistema sanitario de Navarra” This case study reports successful treatment of frontal fibrosing alopecia with daily 2.5mg finasteride in a 77-year-old woman.
August 2016 in “Journal of the Portuguese Society of Dermatology and Venereology” This article discusses two cases of the rare combination of frontal fibrosing alopecia and lichenoid pigmentation in women, but reports no new clinical results.