Frontal Fibrosing Alopecia: State of the Art and Future Directions

    October 2020 in “ International Journal of Research in Dermatology ”
    Joana Resse Lascasas, Joana Silva Peixoto, Sofia Vedor
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    TLDR The review suggests more research is needed to understand Frontal fibrosing alopecia, a condition causing hairline recession in postmenopausal women.
    The 2020 review "Frontal fibrosing alopecia: state of the art and future directions" analyzed 50 publications on Frontal fibrosing alopecia (FFA), a condition characterized by the recession of the frontotemporal hairline, primarily in postmenopausal women. The cause of FFA was unclear, but it was believed to be immune-mediated, with stem cells in the follicle being destroyed by inflammation. Environmental factors like sunscreen use were also associated with a higher incidence of FFA. The disease could stabilize on its own, but hair regrowth was rare. The review highlighted the need for more randomized controlled trials and prospective studies to better understand FFA due to the lack of standardized assessment methods and difficulty in comparing data.
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