38 citations,
June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
35 citations,
December 2020 in “International Journal of Molecular Sciences” Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
34 citations,
June 2020 in “British journal of dermatology/British journal of dermatology, Supplement” Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
30 citations,
January 2020 in “Journal of The American Academy of Dermatology” Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.
29 citations,
February 2010 in “British Journal of Dermatology” Snail1 may contribute to fibrosis in frontal fibrosing alopecia in postmenopausal women.
26 citations,
December 2017 in “Journal of Investigative Dermatology” Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
16 citations,
February 2010 in “Journal of the European Academy of Dermatology and Venereology” Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.
16 citations,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” The document concludes that there are no reliable treatments for frontal fibrosing alopecia, with only temporary benefits from current options.
15 citations,
December 2017 in “Journal of The European Academy of Dermatology and Venereology” Frontal fibrosing alopecia and androgenetic alopecia may be related, with a possible shared cause.
13 citations,
January 2019 in “Skin appendage disorders” FAPD is a possible diagnosis for hair loss in patients of color and requires multiple evaluations for accurate diagnosis.
13 citations,
January 2018 in “International Journal of Dermatology” The study found that treatment improved hair condition in patients with Fibrosing Alopecia in a Pattern Distribution in Chile.
9 citations,
January 2018 in “International Journal of Trichology” A woman's hair loss from graft versus host disease helps understand similar hair loss conditions.
8 citations,
August 2017 in “Skin appendage disorders” Red dots on the upper chest may be an early sign of certain types of hair loss.
7 citations,
August 2021 in “Journal of the European Academy of Dermatology and Venereology” Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.
7 citations,
September 2019 in “Journal of The American Academy of Dermatology” Inflammation and fibrosis are not significantly different in pattern hair loss compared to controls.
6 citations,
October 2019 in “Case Reports in Dermatology” The document concludes that treatment can improve hair growth and symptoms in Fibrosing Alopecia in a Pattern Distribution.
3 citations,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupting YAP signaling in skin cells leads to scar-free healing directed by specific cell signals.
2 citations,
January 2021 in “Journal of The American Academy of Dermatology” A simple scalp scraping can effectively distinguish fibrosing alopecia from androgenetic alopecia with seborrheic dermatitis.
2 citations,
July 2020 in “Giornale italiano di dermatologia e venereologia” A woman with frontal fibrosing alopecia experienced unusual hair growth after using a specific topical lotion.
2 citations,
January 2019 in “Skin appendage disorders” Early diagnosis and quick treatment improve life quality for FFA patients.
1 citations,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
1 citations,
September 2021 in “The Journal of Dermatology” Japanese cases of fibrosing alopecia show a unique age and hair loss pattern, possibly due to racial differences.
1 citations,
July 2018 in “Elsevier eBooks” FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.
1 citations,
March 2012 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Dermoscopy helps diagnose frontal fibrosing alopecia by identifying specific scalp features.
1 citations,
January 2010 in “Springer eBooks” Hair loss in androgenetic alopecia may be due to ongoing tiny inflammation and tissue changes around hair follicles.
August 2024 in “Life Science Alliance” Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.
April 2024 in “Journal of clinical medicine” Effective treatment guidelines for frontal fibrosing alopecia are still unclear.
September 2023 in “International Journal of Dermatology” Younger people are at a higher risk for Fibrosing Alopecia in a Pattern Distribution than previously thought, with common symptoms and possible involvement of mast cells in its development.
April 2023 in “Journal of Investigative Dermatology” The study suggests fibrosing alopecia in a pattern distribution has distinct features and may vary by race.
April 2023 in “Journal of Investigative Dermatology” Radiation treatment causes skin fibrosis by increasing certain fibroblast subpopulations, but using a c-Jun inhibitor or fat grafting can reduce this effect.