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Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Undiagnosed lupus can cause severe complications after epidural anesthesia, leading to muscle weakness and potentially death.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.

Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.

Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Finasteride slows down motherly behavior in first-time pregnant rats.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Licorice has many traditional health benefits, but more research is needed to fully support these claims.

Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.

Eclipta prostrata Linn has many health benefits and is used in traditional medicine.

The document concludes that reactivation of herpesviruses, especially HHV-6, is linked to severe symptoms and complications in drug-induced hypersensitivity syndrome.

DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.

Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.

Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.

Psoriasis is the most common cause of erythroderma, and proper medical follow-up is crucial.

The document concludes that various dermatological treatments and drugs can cause skin reactions and side effects.

Some acne medications have side effects; doctors should educate patients and may not need to do frequent lab tests for all.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Psychotropic medications can cause skin reactions, including severe conditions like SJS and TEN, and it's important for psychiatrists to recognize and manage these side effects.

Ficus carica extract improved fertility in rats and may help with certain health conditions.

Herbal remedies can cause adverse effects and need more safety research.

Mood stabilizers can cause serious skin reactions; careful monitoring and immediate treatment are crucial.

Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.