February 2024 in “Psychoneuroendocrinology” Higher prenatal anxiety is linked to lower cortisol levels in newborns' hair.
January 2019 in “Cell & developmental biology” 3D cultivation and prenatal stem cell exosomes improve stem cell treatment results, especially for hair loss and age-related issues.
April 2017 in “International journal of current advanced research” Pregnant women often have skin changes, but only a small percentage have skin conditions caused by or specific to pregnancy; doctors need to tell them apart for proper treatment.
March 2003 in “BJOG: An International Journal of Obstetrics and Gynaecology” Mothers and newborns with dental fillings have higher mercury in their hair, but adding fillings during pregnancy doesn't raise mercury levels further.
15 citations,
March 1997 in “International Journal of Dermatology” Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
5 citations,
July 2018 in “Experimental Dermatology” The "Punch Assay" can regenerate hair follicles efficiently in mice and has potential for human hair regeneration.
1 citations,
November 2017 The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
1 citations,
October 1996 in “Dermatologic clinics” Adiponectin reduces inflammation and bone loss in joint replacements.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
March 2024 in “Research Square (Research Square)” Twist2 is essential for proper skin healing and hair growth in developing mice.
Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.
3 citations,
March 2023 in “Scientific Reports” Researchers developed a new method to test hair growth drugs and found that adult cells are best for hair growth, but the method needs improvement as it didn't create mature hair follicles.
April 2017 in “Plastic and reconstructive surgery. Global open” Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
20 citations,
September 2021 in “Nature communications” Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
7 citations,
February 2015 in “Journal of comparative pathology” CD8+ T cells play a key role in graft-versus-host disease in certain mice models.
1 citations,
May 2023 in “Fertility and sterility” Men who went through puberty later had lower sperm counts and altered hormone levels, possibly affecting fertility.
253 citations,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
142 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
124 citations,
June 2002 in “Best Practice & Research Clinical Endocrinology & Metabolism” Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.
85 citations,
April 2004 in “Thyroid” Thyroid problems can negatively affect women's reproductive health and pregnancy, and can cause symptoms like fatigue and depression, but not all women with these symptoms need treatment.
44 citations,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
39 citations,
June 1982 in “The BMJ” Blood tests confirmed a baby in the womb had a CMV infection.
36 citations,
April 1990 in “Dermatologic Clinics” Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.
25 citations,
January 2000 in “Hormone Research in Paediatrics” Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
16 citations,
December 2020 in “PloS one” Researchers found WNT10A to be a key gene in developing goat hair follicles.
15 citations,
January 2015 in “Stem cells international” Human hair follicle stem cells can be turned into red blood cells.
15 citations,
September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
15 citations,
January 1999 in “Reproduction Fertility and Development” Merino sheep have fewer wool follicles at birth than before birth.
11 citations,
June 2017 in “Asian-Australasian journal of animal sciences” Fox genes are important for hair growth and development in cashmere goats.
10 citations,
February 2007 in “Current Opinion in Endocrinology, Diabetes and Obesity” Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.