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Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

Etanercept may not prevent alopecia areata from coming back.

Keratin mutations cause skin diseases and could lead to new treatments.

Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Certain chemotherapy drugs can cause permanent hair loss in stem cell transplant patients.

EVG staining is a valuable, simple, and cost-effective method for diagnosing various skin conditions in dermatopathology.

Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

The document concludes that treating tough skin disease in lupus involves sun protection, steroids, antimalarials, and various other therapies chosen based on individual risks and benefits.

Early recognition and treatment of Peripheral Arterial Disease is crucial to improve survival and health outcomes.

Different hair removal methods have pros and cons, and more evidence is needed to prove laser treatments work.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.

Hair growth and health are influenced by stress and hormones.

Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.

Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

There is no standard treatment for the rare Cronkhite–Canada syndrome, which can be fatal and lead to cancer.

Dermoscopy is a good, noninvasive way to see normal cat skin structures and could be useful for check-ups.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.

Epidermal growth factor helps skin and hair regeneration but needs more research for better understanding.

Caffeine may help reduce stress-induced hair loss.

Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.