September 2021 in “Fertility and Sterility” Older men have different fertility histories and factors affecting fertility, suggesting they may benefit from earlier fertility evaluations.
15 citations,
March 2015 in “PloS one” Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
June 2023 in “Medicine and Pharmacy Reports” A woman with a specific mutation causing adrenal gland issues faced fertility problems, but careful hormone therapy helped her manage it successfully.
20 citations,
January 2016 in “Open Journal of Endocrine and Metabolic Diseases” PCOS affects fertility and is linked to obesity and menstrual irregularities; lifestyle changes are recommended for treatment.
5 citations,
January 2018 in “Research Journal of Pharmacy and Technology” Finasteride significantly reduces fertility in male rats.
January 2019 in “Open Access Journal of Nursing” Thai women with PCOS become more aware and change their lifestyle to manage their fertility and symptoms.
October 2024 in “Andrology” Paternal drug exposure can harm fertility, pregnancy outcomes, and offspring health, with specific drugs linked to various reproductive issues.
January 2005 in “Elsevier eBooks” Insulin resistance and hyperinsulinism are linked to fertility issues and can worsen symptoms of PCOS.
January 2022 in “Skin appendage disorders” Finasteride is effective for male hair loss, but it may cause fertility issues, mental health problems, and rarely, breast growth. Regular health checks can reduce the risk of prostate cancer. Patient understanding and involvement in treatment is important.
97 citations,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
67 citations,
April 1988 in “The Journal of Clinical Endocrinology & Metabolism” A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.
April 2012 in “CORD. Coconut research & development/CORD” Coconut leaf vermiwash improves soil health and crop yields in organic farming.
13 citations,
May 1996 in “Archives of Disease in Childhood” Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.
9 citations,
March 2021 in “Hormones” COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.
7 citations,
April 2008 in “Annals of pharmacotherapy/The annals of pharmacotherapy” Acarbose may improve PCOS symptoms and fertility, but more research is needed.
6 citations,
May 2017 in “Nursing standard” The document concludes that PCOS is a complex condition that can reduce fertility and affect self-esteem, but it can be managed with various treatments.
6 citations,
August 2023 in “Fertility and Sterility” The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.
2 citations,
September 2004 in “Fertility and sterility” High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.
January 2024 in “Theranostics” HDAC6 helps keep ovarian follicles dormant, extending female fertility.
November 2017 in “Elsevier eBooks” PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.
209 citations,
March 1998 in “Biochemical and biophysical research communications” Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.
June 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new risk spots for early hair loss were found, which also link to Parkinson's disease and lower fertility. Two genes, FOXA2 and HDAC4, could be new treatment targets. Hair loss might also be connected to heart disease, metabolic syndrome, and prostate cancer.
55 citations,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
14 citations,
January 2013 in “Indian Journal of Endocrinology and Metabolism” Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.
10 citations,
September 2015 in “Folia Histochemica Et Cytobiologica” Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.
5 citations,
October 2012 in “Journal of Midwifery & Women's Health” Healthcare providers should start with simple fertility tests and treatments before referring patients to specialists.
May 2018 in “International journal of clinical obstetrics and gynaecology” N-acetyl cysteine and metformin both improved fertility in women with PCOS equally, but N-acetyl cysteine had fewer side effects.
Certain medications can negatively impact male fertility.
19 citations,
April 2019 in “Journal of Midwifery & Women's Health” Transmasculine individuals on testosterone therapy need tailored contraception and fertility advice due to unique risks and benefits of each contraceptive method.
11 citations,
July 2003 in “The Nurse practitioner” New treatments for PCOS focus on managing symptoms and improving fertility.