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Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Cosmetics enhance beauty, fix defects, and intimidate enemies, with varying cultural standards and alternative methods.

Spironolactone plus finasteride reduces hirsutism more effectively.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.

Hormonal therapies are safe and effective for treating adult women's acne.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Spironolactone might help protect against severe lung problems in COVID-19 patients.

A male with aromatase deficiency improved bone health with estradiol treatment.

Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.

Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.