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Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.

Skin symptoms can indicate endocrine disorders and have various treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Biotin deficiency is not a major cause of hair loss in women, so biotin supplements are not likely to be an effective hair loss treatment.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Skin problems are common and important signs of eating disorders and treating the eating disorder can improve these skin conditions.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Derma rollers show promise for skin improvement and drug delivery, but more research is needed on their safety and effectiveness.

The Egyptian Arabic Skindex-16 is a reliable way to measure how skin diseases affect quality of life in Egyptian patients.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Hair aging and loss are caused by genetics, hormones, environment, and grooming, with treatments like minoxidil effective for certain types of hair loss.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.

Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.

Dermatologists should understand cultural practices and communicate empathetically to effectively treat skin conditions in children and teens of color.

New technologies help us better understand how skin microbes affect skin diseases.