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This study found that L-cystine, D-pantothenat, and miliacin can enhance the metabolic capacity and proliferation of human keratinocytes, with a combination of these additives potentially providing synergistic benefits in growth media.

This study demonstrates that Tp63-expressing epithelial stem cells from non-skin tissues can respond to skin morphogenetic signals and contribute to the formation of hair follicles, sebaceous glands, and epidermis.

TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.

This study found that overexpression of R-spondin 3 in a mice model impaired hair morphogenesis and regeneration by reducing hair matrix progenitor cell proliferation, thus disrupting the Wnt pathway's regulation of stem cells.

This study found that androgens downregulate BMP2 in dermal papilla cells, inhibiting hair follicle stem cell differentiation, while BMP2 addition may restore hair lineage differentiation through the Wnt/β-catenin pathway.

This meeting in Heidelberg highlighted diverse contributions on stem cell research, including pre-clinical and clinical applications, but reported no new experimental results.

This study found that NKIRAS2 expression affects skin tumor suppression and HRAS-driven transformation in mice, indicating its role in carcinogenesis depends on expression level and cellular context.

This study demonstrated the potential of epithelial cell scaffolds fabricated with various materials for effective hair regeneration, highlighting their promising application in tissue engineering for alopecia treatment.

In this study, researchers reported that adenosine stimulated hair shaft elongation in cultured human hair follicles by promoting proliferation and prolonging the anagen phase, suggesting the A2B adenosine receptor in outer root sheath keratinocytes as a promising target for treating hair growth disorders like alopecia.

This study found that basal cell carcinoma cells differentiate along hair follicle lineages and may be influenced by hair follicle cycle modulators for potential therapeutic targeting.

This study concluded that placental mesenchymal stem cells from aborted fetal tissue may serve as an in vitro model for studying spontaneous abortion mechanisms and potential regenerative therapies due to their abnormal gene expression and differentiation capabilities.

This study found that EGFR inhibitors and ligands did not significantly affect the expression of inflammatory biomarkers in cultured sebocytes, except for a notable increase in IL-1 expression with EGF treatment.

This study found that multipotent neural crest stem cells from hair follicles require a full set of reprogramming factors for induced pluripotent stem cell induction, similar to fibroblasts.

This study found that injecting xeno-free, three-dimensional cell masses from human adipose-derived stem cells improved blood perfusion and preserved limb function in mice without causing tumors or toxicity, suggesting potential for treating severe ischemic diseases.

This chapter discusses the concepts of regeneration and homeostasis, noting that in vertebrates, regeneration is limited to certain tissues like liver, blood, and bone.

This study identified three main ethical concerns regarding stem cell use from an Islamic perspective in Malaysia, focusing on embryonic stem cells, aesthetic applications, and therapeutic medicine.

This study found that β-catenin stabilization in specific mammary epithelial lineages leads to cellular changes and the formation of hyperplastic lesions, revealing its role in initiating mammary neoplastic development.

This research describes methods to activate melanocyte stem cells during hair follicle regeneration and to isolate melanocytes from neonatal mouse skin, with the aim of studying melanogenesis for potential clinical applications.

This research presents a comprehensive workflow for producing EMA-compliant autologous keratinocyte-based therapies for wound healing and explores miRNA-mediated regulations in human keratinocytes and adipose-derived mesenchymal stem cells.

In this study, mouse hair follicle stem cells cultured in mouse embryonic fibroblast/keratinocyte serum-free medium exhibited the highest proliferative ability and stronger osteogenic differentiation potential, similar to hair follicle dermal papilla cells.

The abstract reports that non-cultured cellular grafting has become a prevalent and cost-effective method for treating stable vitiligo, with safety and effectiveness confirmed by two decades of studies. It critiques strict legislative oversight, suggesting it might unnecessarily increase costs and limit patient access.

This study found that donor age and culture medium significantly impact the quality of human full-thickness skin models, with implications for their use as animal model alternatives in research.

Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

This study found that induced expression of mir-302 can reprogram human hair follicle cells into induced pluripotent stem cells through a novel epigenetic mechanism involving global demethylation.

This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.

This study demonstrated that enhancing human skin constructs with hair follicles through engineered cell organization and vascularization improved hair growth in immunodeficient mice, suggesting potential advances for treating alopecia and chronic wounds.

Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.

This forum article in BMC Biology discusses evolving views on the concept of the stem cell niche, highlighting varied mechanisms and the need for better understanding of the niche's roles and functions.

This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.