January 2025 in “Archives of Dermatological Research” This research observed that Moracin M, a compound from the Moraceae family, significantly promotes hair growth and angiogenesis via the Wnt signaling pathway in human dermal papilla cells, offering a promising alternative to current hair growth treatments like minoxidil.
July 2023 in “JAAD International” This study describes androgenetic alopecia as a common non-scarring hair loss condition primarily influenced by genetic factors and androgen sensitivity, notably impacting psychosocial well-being, especially in females and younger males seeking treatment.
January 2023 in “Skin appendage disorders” This review discusses the potential of low-dose oral minoxidil as a safe and effective treatment for certain hair disorders, including alopecia, but reports no new clinical results.
November 2021 in “Research Square (Research Square)” This study found that human hair follicle dermal papilla cells grown in a 3D model influenced hair growth and immune pathways more effectively than those grown in a 2D culture.
January 2020 in “Indian Journal of Pharmaceutical Sciences” This review discusses rodent models of human hair loss and highlights the potential of traditional medicinal plants as hair growth promoters, but reports no new clinical results.
1 citations
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June 2023 in “Journal of Cosmetic Dermatology” This study found that while clinical evidence is limited, early preclinical results suggest exosome treatment may enhance hair growth and warrant further research for therapeutic use in alopecia.
34 citations
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April 2001 in “PubMed” This study found that eflornithine HCl 13.9% cream reduces unwanted facial hair growth in women, with effects seen in up to 60% of participants over 4-8 weeks, with mostly minor skin irritation reported.
December 2024 in “Journal of Cosmetic Dermatology” This study found that exosomes derived from platelet-rich plasma show preclinical promise for wound healing but lack sufficient data for other dermatological uses like hair growth and skin rejuvenation.
1 citations
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March 2023 in “Journal of Drugs in Dermatology” This study reported that dupilumab, a human monoclonal antibody, induced hair regrowth in patients with alopecia totalis, suggesting its potential as a treatment for this condition.
3 citations
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January 2023 in “Regenerative Medicine” This review discusses the potential role of exosomes in aesthetic medicine for skin rejuvenation and hair restoration, but reports no new clinical findings and emphasizes the need for further studies with regulatory oversight.
1 citations
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December 2024 in “Indian Dermatology Online Journal” This research notes that biologics and small molecules are effective for treating nail psoriasis and alopecia areata, albeit with precautions for adverse events, but no clinical trials have been published for their use in treating nail lichen planus and atopic dermatitis.
1 citations
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November 2022 in “Journal of Dermatological Treatment” This review discusses the use of platelet-rich plasma for various dermatologic conditions but reports inconsistent evidence and a lack of standardized protocols; patients often report high satisfaction despite mixed clinical outcomes.
1 citations
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April 1998 in “Dermatologic Clinics” This article outlines the evolving landscape of surgical dermatology and highlights the promising future as new techniques continue to emerge, but it presents no new research results.
January 2026 in “Clinical Dermatology Review” This study found that platelet-rich plasma therapy significantly improved hair density, diameter, and reduced inflammation in androgenetic alopecia patients compared to placebo, though individual responses varied.
December 2024 in “IntechOpen eBooks” This source discusses drug repurposing, which seeks new therapeutic uses for existing drugs, emphasizing its benefits like faster development, reduced costs, and novel treatments for unmet medical needs. The chapter outlines current trends and future perspectives in drug discovery through repurposed drugs.
This study outlines treatment strategies for autoimmune alopecia areata, detailing that while mild cases may resolve on their own, severe cases often require intervention, with new JAK inhibitors like baricitinib and ritlecitinib emerging as promising treatments for those not responding to traditional therapies.
August 2023 in “Journal of Dermatological Treatment” This systematic review concluded that mesotherapy shows potential for improving hair growth outcomes, yet lacks standardized regimens and requires further large-scale trials to establish its efficacy and safe use.
April 2023 in “Journal of Pakistan Medical Association” This source reports that clinical trials found oral baricitinib significantly improved hair regrowth in patients with severe alopecia areata, with 38.8% achieving at least 80% scalp hair coverage after 36 weeks on a 4-mg dose, compared to 6.2% with placebo in trial 1.
August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identifies diltiazem as a promising repurposed drug for treating influenza, supported by its antiviral activity and gene modulation effects, leading to a Phase II clinical trial authorization.
November 2013 in “Journal of clinical & experimental dermatology research” This narrative review discusses the potential of urinary bladder matrix as a bio-scaffold in hair restoration but provides no new clinical results or trials; it highlights regenerative technology and suggests further exploration.
6 citations
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May 2023 in “Drugs” This study reports that baricitinib was more effective than placebo in promoting hair growth in adults with severe alopecia areata after 36 weeks of treatment in clinical trials.
86 citations
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January 2021 in “Gland Surgery” This review article found no concrete evidence supporting the existence of "silicone implant illness" as a new syndrome, despite the association of various symptoms with breast implants which are considered safe according to current evidence.
42 citations
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August 2013 in “International Journal of Women's Health” This review discusses the current therapeutic options for female pattern hair loss and emphasizes the need for managing patient expectations of permanent regrowth, reporting no new clinical results.
34 citations
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February 2015 in “Frontiers in Cellular Neuroscience” This study identified new genes and compounds affecting hair cell survival during ototoxin exposure using the zebrafish model, potentially aiding in understanding and preventing hearing loss and balance disorders in humans.
18 citations
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February 2025 in “Macromolecular Rapid Communications” In this review, researchers explored thermo-responsive polymers and their applications in nanomedicine, highlighting their role in targeted drug delivery, gene therapy, and imaging, enabled by their temperature-sensitive phase transitions to ensure localized therapeutic action and minimize damage to healthy tissues.
18 citations
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October 2020 in “Radiation Research” This review discusses the similarities between COVID-19 and acute radiation syndrome, highlighting their shared inflammatory responses and suggesting that insights from radiation biology could inform COVID-19 research and treatment approaches; it reports no new clinical results.
17 citations
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November 2021 in “Journal of Cosmetic Dermatology” This review discusses treatment options for androgenetic alopecia, highlighting the need for personalized, evidence-based approaches but reports no new clinical results.
9 citations
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July 2024 in “JAAD reviews.” This review discusses the role of extracellular vesicles in dermatology for therapeutic, diagnostic, and prognostic purposes, highlighting the lack of validated findings and the necessity for more rigorous clinical trials.
2 citations
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June 2022 in “Phytomedicine” This study found that Shi-Bi-Man, a hair health supplement, significantly promoted hair growth in mice, likely through activation of the FGF signaling pathway.
1 citations
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December 2023 in “Molecules/Molecules online/Molecules annual” This review summarized the latest knowledge suggesting that Janus kinase inhibitors may have therapeutic potential for treating skin diseases like atopic dermatitis and psoriasis, especially when conventional therapies do not work.