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Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Fat cells help recruit healing cells and build skin structure during wound healing.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

The Rotterdam Study aims to understand various diseases in older adults.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Telogen effluvium is a common type of hair loss that can resolve on its own or become chronic, with treatment depending on early diagnosis.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

PEVs improve minoxidil skin penetration, increasing hair growth.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.