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Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

A genetic duplication on chromosome 5 was linked to a woman's unique combination of medical conditions.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

A 3-month treatment improved PCOS symptoms and reduced certain immune proteins.

Eating disorders can cause various hair problems, and while hair loss in these disorders is linked to metabolic syndrome, treatment focuses on specific medications and lifestyle changes for the syndrome.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.