72 citations,
April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
68 citations,
April 2002 in “Journal of Human Nutrition and Dietetics” The intensive conventional diet with exercise led to better long-term weight loss and health improvements than the very low calorie diet in obese type 2 diabetics.
61 citations,
February 2001 in “American Journal of Obstetrics and Gynecology” Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.
54 citations,
November 2017 in “Scientific Reports” The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
52 citations,
February 2018 in “Diabetology & Metabolic Syndrome” Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.
50 citations,
January 2018 in “Acta physiologica” Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.
49 citations,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.
47 citations,
June 2016 in “JAMA Dermatology” Men with early hair loss have similar hormone levels to women with PCOS, possibly increasing risk of obesity and heart issues.
45 citations,
January 2013 in “Journal of Human Reproductive Sciences” Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.
45 citations,
February 2012 Obese women with PCOS are more likely to have fatty liver disease.
42 citations,
April 2011 in “European Journal of Dermatology” Early balding men may have insulin resistance, but lifestyle changes can help.
40 citations,
September 2018 in “Journal of the American Academy of Dermatology” Tofacitinib helped some young children with severe hair loss grow their hair back without bad side effects.
39 citations,
September 2000 in “Obstetrics and Gynecology Clinics of North America” Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.
38 citations,
May 2006 in “Archives of Gynecology and Obstetrics” Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.
37 citations,
October 2017 in “Clinical and Experimental Dermatology” Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.
36 citations,
March 2002 in “Journal of Biological Chemistry” Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
35 citations,
April 2011 in “International Journal of Dermatology” No true link between AGA and insulin resistance, but coexistence may worsen AGA.
34 citations,
July 2014 in “Indian Dermatology Online Journal” Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.
32 citations,
January 2007 in “KARGER eBooks” Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.
32 citations,
December 1969 in “The Lancet” Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.
31 citations,
January 2014 in “Clinical Endocrinology” The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.
29 citations,
January 2011 in “Journal of Obstetrics and Gynaecology” Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.
28 citations,
July 2017 in “Journal of Endocrinological Investigation” Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
25 citations,
January 2013 in “International Journal of Trichology” Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.
24 citations,
January 2013 in “Indian Dermatology Online Journal” Balding people may have higher heart disease risk.
23 citations,
March 1994 in “Fertility and sterility” Most patients improved with oral contraceptives, but some needed additional treatment.
22 citations,
January 2006 in “International Journal of Andrology” Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.
22 citations,
June 2005 in “Clinical Oncology” Orlistat might block the body's ability to absorb thyroid medication.
21 citations,
September 2017 in “Journal of Obstetrics and Gynaecology Research” Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.
21 citations,
November 2015 in “Archives of Gynecology and Obstetrics” Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.