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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Oestrogens are key for bone growth during puberty in both boys and girls.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Too much androgen can cause hair loss; finasteride may help.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.