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research A umbilical cord blood-derived exosome product simulates hair growth through laminin V and collagen XVII: an ex vivo study
This study found that Limelight (CB-EVs) exosomes significantly promoted hair elongation ex vivo without cytotoxicity, suggesting potential as a safe and effective hair growth therapy.
research Skin and Adnexa of the Laboratory Mouse
research Author response: ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas
This study found that super-enhancers play a crucial role in driving malignant progression in squamous cell carcinoma stem cells through a regulatory network involving ETS2 transcription factors, highlighting the potential link between high ETS2 levels and poor patient outcomes in head and neck cancers.
research 090 Reactive lipids from the secretome of senescent fibroblasts modify the extracellular matrix with functional consequences for resident cells
Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
research Case Report: Compound heterozygous variants in LSS and TSPEAR genes causing hypotrichosis type 14 complicated with ectodermal dysplasia type 14
This study suggests that coexisting LSS and TSPEAR variants might contribute to a complex phenotype of congenital hypotrichosis and ectodermal abnormalities in a child, and highlights the need for cautious interpretation of genotype-phenotype links and the potential value of broader genetic testing.
research Glossary
This abstract provides definitions and descriptions of terms related to insects, arachnids, and other invertebrates, but includes no new research findings.
research Emollients: application of topical treatments to the skin
This article discusses the importance of nurses' understanding of topical emollient therapy for patients with eczema, but it does not provide new clinical results.
research Ectoin attenuates cortisone‐induced skin issues by suppression GR signaling and the UVB‐induced overexpression of 11β‐HSD1
In this study, researchers found that Ectoin, derived from halophilic bacteria, can mitigate stress-related skin damage by reducing cortisone's inhibitory effects on essential skin proteins and decreasing UVB-induced glucocorticoid activity, highlighting its potential as a preventative agent for stress-induced skin issues.
research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.
research Tissue expansion for correction of alopecia in a child with hypohidrotic ectodermal dysplasia
This letter discusses tissue expansion for correcting alopecia in a child with hypohidrotic ectodermal dysplasia, but provides no new experimental results.
research 602 Sox13 is a novel marker for hair follicle development and differentiation
Sox13 is a new marker for early hair follicle development and differentiation.
research Viewpoint 7
This review discusses the multifunctional role of subcutaneous adipocytes, their contribution to metabolic and pathological processes, and reports no new experimental results; it suggests potential protective roles against metabolic syndrome.
research LB1076 Using the frog embryonic epidermis as a model to study desmosome function during development
This study found that the desmosomal protein desmoplakin is crucial for proper epidermal morphogenesis and radial intercalation in developing Xenopus embryos, affecting keratin organization and ectodermal structures.
research 1346 Functional roles of Krox20 (Egr2) in Epithelial Stem Cells
This study found that KROX20 is crucial for hair follicle development and epidermal homeostasis, as its deletion in skin epithelial cells led to hair loss and increased epidermal thickness.
research Skin cell-derived extracellular vesicles: a promising therapeutic strategy for cutaneous injury
This review discusses the role of extracellular vesicles from specific skin cells in wound healing, emphasizing their potential in regenerative medicine and reporting no new experimental results.
research Extracellular Vesicles for Cosmetic Applications
This review discusses the potential of extracellular vesicles from various sources for skin rejuvenation and cosmetic use, noting promising results, especially with mesenchymal stem cell-derived vesicles, but reports no new clinical results.
research Novel insights into hair structure and the effects of chemical stressors on hair and skin using label-free advanced light microscopy
This study developed new label-free imaging methods to analyze human hair, identifying distinct chemical environments within cuticle layers and changes in hair structure caused by depilatories, while showing that the treatments tested did not significantly affect skin cell differentiation or proliferation.
research A novel method for visualizing hair lipids at the cell membrane complex: Argon sputter etching/scanning electron microscopy1
This study found that scanning electron microscopy with argon sputter etching visualizes hair lipids at the cell membrane complex as distinctive convex structures, shedding light on their role and localization in human hair.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.
research Unsaturated Halogenated Hydrocarbons
This review discusses the uses and toxicological data of eleven unsaturated halogenated hydrocarbons, including dichloroacetylene, allyl chloride, hexachlorobutadiene, β-chloroprene, vinyl chloride, trichloroethylene, and perchloroethylene, but presents no new findings.
research Comprehensive Program Planning for the Integration of 21st Century Learning Center After-School Programs with Regular Day Programs and Community Partners.
This case report describes a rare occurrence of ectodermal dysplasia features in a 14-year-old with MBTPS1 gene variants, expanding the known spectrum of related disorders.
research Visible characteristics and structural modifications relating to enlarged facial pores
This study found that enlarged facial pores in women show distinct microstructural alterations, including regular keratinocyte arrangement and irregular dermo-epidermal junctions, highlighting changes in skin tension linked to pore enlargement.
research LEXICAL FEATURES OF BRITISH SLANG AND DESCRIPTION OF ITS WORD FORMATION
This article reviews the lexical features and development of modern British slang, exploring linguistic, cultural, and social group specifics but reports no new research results.
research Dissection of a Complex Enhancer Element: Maintenance of Keratinocyte Specificity but Loss of Differentiation Specificity
In this study, researchers identified distinct chromatin regions and regulatory elements that drive keratinocyte-specific gene expression, highlighting complex enhancer modules influencing skin epithelium through a combination of transcriptional activators and repressors.
research The Influence of exogenous zinc on the random flap
This study found that exogenous zinc improved the viability of ultralong random skin flaps in Wistar rats by reducing oxidative damage and increasing protective protein levels.
research The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review
This review discusses the role of extracellular vesicles in psoriasis pathogenesis and their potential as therapeutic agents or drug delivery systems, but it reports no new clinical findings.
research Coordinated Regulation of Signaling Pathways by Stem Cell-Derived Extracellular Vesicles: A Promising Strategy Against Skin Photoaging
This study highlights the potential of stem cell-derived extracellular vesicles to treat UV-induced skin damage by modulating key signaling pathways, though challenges like EV composition variability and skin barrier penetration remain, underscoring the need for further research into optimized delivery methods for effective therapies.
research Transcriptome analyses of reprogrammed feather / scale chimeric explants revealed co-expressed epithelial gene networks during organ specification
This study reveals that β-catenin and retinoic acid are key regulators in the gene networks controlling the fate of skin appendages, such as scales and feathers.
research A Clinician's approach to the investigation of otitis externa
This article highlights causes of otitis externa in small animals and proposes an investigative approach; it reports no new findings.