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Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Treatments for melanin disorders exist, but more effective options needed.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Treating cystoid macular oedema in uveitis is difficult and risky.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Wnt10b helps blood stem cells grow after injury.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.