research Kin-Cohort Analysis of LRRK2-G2019S Penetrance in Parkinson's Disease
The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
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research Role of Androgens in Female-Pattern Androgenetic Alopecia, Either Alone or Associated with Other Symptoms of Hyperandrogenism
Androgens significantly affect female hair loss, and hormonal treatments may help.
research Morphological Changes in Human Scalp Hair Roots During Protein Deprivation
Not eating enough protein can cause hair roots to shrink and lose color, and hair to become thinner.
research Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny During Cutaneous Wound Repair
The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.
research Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia
New genes found linked to balding, may help develop future treatments.
research Putative Role for Insulin Resistance in Depression Risk in Polycystic Ovary Syndrome
Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
research Steroid Plant Hormones: Effects Outside the Plant Kingdom
Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
research A Preliminary Study of Finasteride in Tourette Syndrome
Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.
research Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality
Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
research Adaptations in the Structure and Innervation of Follicle-Sinus Complexes to an Aquatic Environment as Seen in the Florida Manatee (Trichechus Manatus Latirostris)
Manatee whiskers are specially adapted for touch in water.
research Phosphatidic Acid Has Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells
Phosphatidic acid may help hair grow by affecting cell growth pathways.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal, and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research Acorus Calamus: A Bio-Reserve of Medicinal Values
*Acorus calamus* has many medicinal benefits but needs more safety research.
research Value of Trichoscopy Versus Trichogram for Diagnosis of Female Androgenetic Alopecia
Trichoscopy is better than trichogram for diagnosing female hair loss.
research Lipid Levels in Patients with Lichen Planus: A Case-Control Study
People with lichen planus have higher bad cholesterol and lower good cholesterol, increasing their risk for heart disease.
research FGFR2 Is Associated With Hair Thickness In Asian Populations
A gene variation is linked to hair thickness in Asians.
research Analysis of Structural Changes in Permanent Waved Human Hair Using Raman Spectroscopy
Permanent waving weakens hair by altering its protein structure.
research α3β1-Integrin Regulates Hair Follicle But Not Interfollicular Morphogenesis in Adult Epidermis
α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
research Rosemary Extracts Containing Carnosic Acid and Carnosol Are Potent Quorum Sensing Inhibitors of Staphylococcus Aureus Virulence
Rosemary extracts with carnosic acid and carnosol can reduce the harmfulness of Staphylococcus aureus without stopping its growth.
research Lymphatic Vessels Interact Dynamically with the Hair Follicle Stem Cell Niche During Skin Regeneration In Vivo
Lymphatic vessels are essential for hair follicle growth and skin regeneration.
research Establishment of an In Vitro Organoid Model of Dermal Papilla of Human Hair Follicle
Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
research Oral Tofacitinib Monotherapy in Korean Patients with Refractory Moderate-to-Severe Alopecia Areata: A Case Series
Tofacitinib is effective and safe for treating severe hair loss in Korean patients.
research Optimization of Ultrasonic-Assisted Extraction of Total Saponins from Eclipta Prostrasta L. Using Response Surface Methodology
The best way to extract saponins from Eclipta prostrasta is using 70% ethanol, at 70°C for 3 hours with a 14:1 liquid to solid ratio.
research Tumor Mapping in Two Large Multigenerational Families With CYLD Mutations
CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
research Hair Growth Induction: Roles of Growth Factors
EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
research Female Androgenetic Alopecia: An Update on Diagnosis and Management
FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.
research Curtailing Polycystic Ovary Syndrome: A Review of International Evidence-Based Guidelines and Implications
Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
research Functional Skin Grafts: Where Biomaterials Meet Stem Cells
Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
research Genome-Wide Meta-Analysis Implicates Mediators of Hair Follicle Development and Morphogenesis in Risk for Severe Acne
Genetic variations affecting skin structure play a key role in severe acne.
research Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration
Hoxc genes control hair growth through Wnt signaling.