9 citations
,
June 2014 in “Journal of Craniofacial Surgery” The authors concluded that using an expanded temporoparieto-occipital scalp flap for sideburn reconstruction provides satisfactory hair direction and inconspicuous scars in both the donor and recipient areas, with few complications.
6 citations
,
June 2016 in “Journal of Craniofacial Surgery” This study reports that using a combined approach of free osteoseptocutaneous fibula flap and temporal artery-based scalp flap provided satisfactory aesthetic and functional outcomes in reconstructing gunshot-inflicted composite mandibular defects in males.
4 citations
,
November 2015 in “Aesthetic Plastic Surgery” Using tissue expanders for scalp reconstruction in patients with extensive Aplasia Cutis Congenita is effective and has minimal complications.
11 citations
,
July 2017 in “Regenerative Medicine” This study found that the patch assay effectively reconstituted mature hair follicles using culture-expanded human fetal cells and may serve as a method to assess cell trichogenicity.
8 citations
,
March 2009 in “Aesthetic Plastic Surgery” This study found that the "flying-wings" expanded scalp flap technique effectively restored hemiscalp defects in children following burns, achieving pleasing aesthetic results and proper hair growth direction with minimal complications.
2 citations
,
December 2019 in “Archives of Craniofacial Surgery” This report describes successful scalp resurfacing using serial tissue expansion with a tissue expander in two patients with large lesions, suggesting this method can effectively treat extensive hairless scalp areas.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that targeting skin-infiltrated memory phenotype T cells could offer a new therapeutic approach to manage lymphopenia-related diseases like graft-versus-host disease and immune reconstitution inflammatory syndrome.
This case study reports successful treatment of partial scalp alopecia secondary to a repaired occipital encephalocele using the tissue expansion technique.
August 2026 in “Transplantation and Cellular Therapy” This study found that serum-free expanded hair follicle mesenchymal stem cells (hfMSCs), derived from hair plucking, significantly improved cartilage repair in a murine model despite minimal engraftment, suggesting their effectiveness through a paracrine mechanism.
August 2025 in “مجلة جامعة الحضارة للبحوث التطبيقية والإنسانية” This study conducted in Yemen involving 50 patients found that tissue expansion was effective for correcting scars and defects from post-burn and post-war injuries, achieving a 78% satisfaction rate with minimal complications.
3 citations
,
March 2023 in “Cell Biology International” In this study, ASC-enriched autologous fat grafting was found to be more effective and satisfying than conventional fat grafting for treating facial contour deformities with hyperpigmentation.
16 citations
,
January 2011 in “Archives of Dermatological Research” This study identified 77 genes with significant expression changes in expanded human skin, suggesting possible mechanisms for skin regeneration during tissue expansion, including previously unreported genes like HOXA5, HOXB2, and AP1.
11 citations
,
February 2019 in “Stem cells international” In this study, researchers found that while both hair follicles and skin dermis-derived neural crest stem cells are suitable for large-scale manufacturing, skin dermis cells grow faster and are easier to obtain.
3 citations
,
April 2025 in “Journal of Clinical Epidemiology” This study found that non-blinded assessors in randomized clinical trials exaggerated the effects of experimental interventions by about 29% compared to blinded assessors, indicating a significant potential for observer bias in treatment evaluations.
February 2024 in “Frontiers in physiology” This study examines the role of hair follicle stem cells in epidermal regeneration during skin soft tissue expansion, proposing a potential method for their cellular and molecular regulation.
1 citations
,
October 2021 in “PubMed” This case report describes a 43-year-old woman with scarring burn alopecia treated with tissue expansion and local flap reconstruction, who experienced reversible acute hair loss (Telogen Effluvium) after the procedure.
30 citations
,
June 2008 in “Dermatologic Surgery” In this study, the SAFE System for follicular unit extraction demonstrated a favorable average follicle transection rate of 6.14% and is accessible for physicians with basic technical skills, showing promise for wider adoption.
6 citations
,
May 2013 in “PloS one” This study found that the Foxn1(-/-) nude phenotype significantly influences epithelial progeny in skin, with notable changes in stem cell niches not achievable in other models.
This study found that conditioned media from SHED stem cells cultured in STK2 media significantly stimulated hair growth in mice more effectively than media from HFSCs.
43 citations
,
December 2013 in “Stem Cells” Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.
1 citations
,
August 2020 in “Open Access Macedonian Journal of Medical Sciences” This review summarizes current knowledge on cutaneous symptoms in COVID-19, emphasizing their potential prognostic and therapeutic implications, but reports no new clinical findings.
7 citations
,
April 1994 in “Archives of Otolaryngology-head & Neck Surgery” This article discusses scalp tissue expansion as a superior reconstructive option for large defects over traditional skin grafts and flap methods, but reports no new clinical outcomes.
5 citations
,
July 2019 in “Atlas of the Oral and Maxillofacial Surgery Clinics” This article discusses challenges and limitations of using simple tissue mechanics for repairing head and neck skin defects in trauma and does not report new findings; it highlights potential problems with routine methods.
2 citations
,
January 2017 in “Recent clinical techniques, results, and research in wounds” This study found that adding galeotomies to subgaleal tissue expander placement for post-burn alopecia resulted in faster scalp expansion and reduced complications of expander extrusion.
1 citations
,
December 2017 in “JAMA Facial Plastic Surgery” This study found that both PHDPE and ePTFE hair-bearing scaffolds were well tolerated in a rat model, with minimal infection or extrusion, though artificial hair showed progressive loss over time.
September 2024 in “Journal of Cutaneous and Aesthetic Surgery” This case report detailed a successful treatment involving contracture release and expanded neck flap reconstruction for a patient with severe neck contracture and beard alopecia from past thermal burns, highlighting improved skin quality and hair regrowth following follicular unit extraction.
July 2007 in “Clinical Risk” A woman got severe scalp burns from a salon's improper hair bleaching treatment.
July 1998 in “Dermatologic Surgery” Various techniques and tools for hair restoration were presented in 1998, including a mathematical model for donor area, use of lasers in surgery, methods for controlling grafted hair direction, and ways to increase graft yield. Satisfaction rates were around 39%, and studies showed trauma and dehydration can damage hair follicles.
31 citations
,
March 2009 in “Archives of Facial Plastic Surgery” This retrospective study found that a hairline-lowering technique effectively advanced the female hairline by an average of 2.1 cm with high patient satisfaction and minimal complications over 20 years.
6 citations
,
July 2017 in “Clinics in Plastic Surgery” This article reviews the management of head and neck burns across different phases but presents no new clinical results.