January 2025 in “Anais Brasileiros de Dermatologia” Male pattern baldness worsens with age and can be treated with medications like minoxidil and finasteride, but side effects and personalized care are important.
22 citations,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
9 citations,
January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
1 citations,
November 1996 in “Journal of Cutaneous Medicine and Surgery” Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
34 citations,
February 2018 in “Drug Design Development and Therapy” Bimatoprost is safe and effective for improving eyebrow hair.
58 citations,
April 1998 in “Journal of biological chemistry/The Journal of biological chemistry” CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.
65 citations,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
108 citations,
July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
89 citations,
May 1999 in “Allergy” The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.
96 citations,
December 2018 in “Immunity” Targeting TGFβ can improve skin immunity in older people.
18 citations,
February 2022 in “Cell Death Discovery” ECM1-modified stem cells can effectively treat liver cirrhosis.
75 citations,
October 1999 in “European journal of endocrinology” Finasteride is a safe, effective treatment for hirsutism with fewer side effects.
69 citations,
August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.
April 2024 in “Scientific reports (Nature Publishing Group)” Rosemary and neem extract may be an effective natural treatment for dandruff and hair loss.
14 citations,
December 2018 in “The American journal of pathology” Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.
50 citations,
October 1986 in “European journal of pediatrics” A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
8 citations,
October 1988 in “Clinics in Dermatology” Current research explores hair growth drugs, while future research aims for personalized treatments.
4 citations,
January 2021 in “Skin appendage disorders” Washing hair daily is better and preferred, with no negative effects.
101 citations,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
7 citations,
May 2017 in “Behavioural brain research” Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.
105 citations,
May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating TRPV3 stops human hair growth.
68 citations,
May 2011 in “European Journal of Dermatology” Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
28 citations,
December 2018 in “Plant, cell & environment/Plant, cell and environment” A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.
64 citations,
March 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” GPRC5D is linked to the formation of hair, nails, and certain tongue areas.
17 citations,
January 2006 in “Veterinary Dermatology” Topical melatonin and brushing did not affect hair regrowth in Siberian Huskies.
10 citations,
January 2009 in “Elsevier eBooks” Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
341 citations,
November 2009 in “The FASEB Journal” Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
13 citations,
December 2018 in “Development, Growth & Differentiation” Sex hormones, especially estradiol, can change chicken feather shapes and colors.
October 2023 in “Journal of Cosmetic Dermatology” A synthetic octapeptide may help promote hair growth and counteract hair loss.