Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case report describes a patient with hemophagocytic lymphohistiocytosis who developed hypertrichosis and eyelash trichomegaly, likely linked to cyclosporine-A and prednisolone therapy, with expected resolution after stopping treatment.

This review explores how mesenchymal stem cells and their extracellular vesicles may treat various skin diseases by modulating immune responses and promoting healing, though further clinical trials are needed to confirm their safety and efficacy in practice.

This article reports no new clinical findings but discusses two rare dermatological conditions, trichostasis spinulosa and eruptive vellus hair cysts, and their simultaneous occurrence.

This report describes a Cronkhite-Canada syndrome patient with severe sepsis and disseminated intravascular coagulation successfully treated using combined therapies, including recombinant human soluble thrombomodulin.

This review discusses the hedgehog signaling pathway's role in cutaneous tumors and hematological disorders, highlighting its potential as a therapeutic target, but reports no new clinical findings.

This review discusses fixed drug eruption (FDE) potentially linked to finasteride and emphasizes dermatologists' need to recognize its possible occurrence due to the drug's widespread use, but reports no new clinical results.

This study found that combining ultrasound with a GelMA hydrogel able to deliver mesenchymal stem cell-derived vesicles significantly improved wound healing in a mouse model by enhancing fibroblast activity, promoting re-epithelialization, and facilitating hair follicle regeneration, highlighting a novel approach to skin regeneration therapy.

This abstract reflects on the author's journey in hair restoration surgery since 1986, but it presents no new research findings.

This study found increased H2O2 levels and decreased E-cadherin levels in vitiligo patients compared to controls, suggesting oxidative stress and compromised cell adhesion may impact the pigmentary system in vitiligo-affected skin.

This study found that HFV70 cryogels, made from Flammulina velutipes extract and hydroxyethyl cellulose, effectively promoted rapid hemostasis and tissue regeneration in full-thickness skin defects in rats, demonstrating improved hemocompatibility, cytocompatibility, antimicrobial, and antioxidant properties.

This study found that the HoxC gene cluster plays a critical role in the development of ectodermal organs, including hair and nails, with mammalian-specific enhancers increasing transcription levels during development.

This case report describes a 29-year-old male with relapsing hepatitis A, a rare complication of acute hepatitis A virus infection, characterized by prolonged elevated liver chemistries and persistent HAV IgM, managed conservatively.

This study reports a case of GGCX syndrome in a 55-year-old Japanese male, characterized by PXE-like symptoms and coagulation deficiency, with an unreported phenotype of possible spinocerebellar degeneration.

This study found that in noise-exposed FVB/NJ mice and cell models, ivacaftor reduced oxidative stress and hearing damage by maintaining CFTR function and increasing Nrf2 expression, suggesting its potential for treating noise-induced hearing loss.

In this study, a Chinese Han family with hereditary vitamin D-resistant rickets was found to have a homozygous missense mutation in the VDR gene, and the affected individual uniquely responded well to treatment with oral calcium and low-dose calcitriol.

This study suggests that pretreatment with a PPAR-γ modulator may prevent damage to hair follicle stem cells caused by a chemotherapy metabolite, potentially offering a strategy to mitigate permanent chemotherapy-induced alopecia.

Acyclovir can prevent rejection of skin grafts in herpes-related lip leucoderma.

This study observed that numerical chromosomal aberrations were more common in men with severe male factor infertility and azoospermia compared to those with other sperm quality issues, while chromosomal translocations were significantly associated with oligoasthenozoospermia, highlighting important genetic counseling considerations.

In this study, researchers found that using electromagnetic radiation in the EHF range enhanced the engraftment of skin flaps in rats by improving microcirculation and reducing necrosis, with greater effects observed when paired with systemic ozone therapy.

This review highlights the evolution of forensic genetics from basic DNA analysis to complex genome-wide studies, enabling insights into personal traits, ancestry, and habits, and suggests future advancements through technologies like CRISPR and AI.

This review found that current forensic DNA phenotyping panels for biogeographical ancestry and visible traits face significant limitations due to inconsistencies in terminology, genetic understanding, and genotyping technologies, highlighting the need for harmonization and further research.

This discussion highlights the potential of next-generation sequencing in forensic science for predicting phenotypic traits from DNA samples, but reports no new clinical results and underscores ongoing ethical and legal challenges.

The authors concluded that steatocystoma multiplex is a rare dermatological condition with poor treatment outcomes, emphasizing the importance of early recognition and psychological support for affected individuals.

This review found that while forensic DNA phenotyping and health applications for pigmentation genetics show potential, factors like phenotype definition and population diversity present challenges to accurate genotype-to-appearance predictions.

This case report describes a 53-year-old woman with a rare presentation of trichostasis spinulosa on her breast and abdomen, featuring itchy, comedo-like lesions. Dermoscopy revealed diagnostic features that may eliminate the need for a biopsy, highlighting the potential for non-invasive diagnosis in such cases.

This article reports that while surgical excision is often the best treatment for SCC, intralesional cidofovir also showed success without systemic toxicity in the case discussed.

This study identified two novel mutations in the CDH3 gene causing HJMD in a Chinese patient, expanding the genetic and phenotypic understanding of the disorder.

This article describes protocols for isolating and expanding human epidermal neural crest stem cells and discusses their potential for cell-based therapies in regenerative medicine, but reports no new clinical results.

This study found that high dose rate electronic brachytherapy was effective for non-melanoma skin cancer, with no recurrences and good to excellent cosmesis up to three years post-treatment.

BOOST is a promising, easy-to-use treatment for diabetic foot ulcers that improves healing by reducing inflammation and promoting blood vessel growth.