research FDA Declines Approval of Testosterone Drug for Third Time
The FDA rejected a testosterone drug again due to safety concerns.
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research Investigation of the Cutaneous Penetration Behavior of Dexamethasone Loaded to Nano-Sized Lipid Particles by EPR Spectroscopy, and Confocal Raman and Laser Scanning Microscopy
Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.
research Pharmacovigilance-Based Drug Repurposing: Searching for Putative Drugs With Hypohidrosis or Anhidrosis Adverse Events for Use Against Hyperhidrosis
Certain existing drugs, like glycopyrronium and botulinum toxin type A, may help treat excessive sweating.
research The Effects of Methylated Flavonoids on Depression-Like Activity and Pro-Inflammatory Cytokine Thresholds in Mice Induced by Repeated Finasteride Administration
Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
research Valproic Acid Reduces Hair Loss and Improves Survival in Patients Receiving Temozolomide-Based Radiation Therapy for High-Grade Glioma
Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.
research Can AMH Levels Distinguish LOCAH from PCOS Among Hirsute Women?
AMH levels can't reliably tell the difference between LOCAH and all types of PCOS in women with excessive hair growth.
research Serum AMH Levels in the Differential Diagnosis of Hyperandrogenemic Conditions
Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
research A Disease-Causing Novel Missense Mutation in the ST14 Gene Underlies Autosomal Recessive Ichthyosis with Hypotrichosis Syndrome in a Consanguineous Family
A new mutation in the ST14 gene causes a rare skin and hair disorder in a specific family.
research Investigation and Analysis of 1030 Primary Hair Transplantation Cases: A Retrospective Study
The study found that hair transplant complications are rare, with swelling being the most common issue.
research Comparison of Stratum Corneum Penetration and Localization of a Lipophilic Model Drug Applied in an O/W Microemulsion and an Amphiphilic Cream
The microemulsion delivered the dye deeper into the skin than the cream.
research Plasma Rich in Growth Factors for the Treatment of Androgenetic Alopecia
PRGF treatment safely and effectively helps hair loss.
research Comparison of Two In Vitro Models for the Analysis of Follicular Penetration and Its Prevention by Barrier Emulsions
Pig ear skin is better than human skin for testing how well barrier creams block allergens from entering hair follicles.
research Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix
CIP/KIP proteins help stop cell division and support hair growth.
research Botulinum Toxins in Medical and Cosmetic Dermatology
Botulinum toxins are safe for various medical and cosmetic uses, but more research is needed for long-term safety and effectiveness in hair growth treatments.
research Use of Topical Minoxidil, 17α-Estradiol, and Hydrocortisone Butyrate in Frontal Fibrosing Alopecia
A lotion with minoxidil, hydrocortisone butyrate, and 17a-estradiol can improve or stabilize Frontal Fibrosing Alopecia in some cases, but there's no universally-accepted treatment yet.
research Inhibition of SARS-CoV-2 Entry Through the ACE2/TMPRSS2 Pathway: A Promising Approach for Uncovering Early COVID-19 Drug Therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research The Quality of European Dermatological Guidelines: Critical Appraisal of the Quality of EDF Guidelines Using the AGREE II Instrument
European dermatological guidelines vary in quality, with some highly rated, but improvements are needed in applicability and consistency.
research The Rotterdam Study: 2016 Objectives and Design Update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research The Rotterdam Study: 2014 Objectives and Design Update
The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
research Prominent Cutaneous Manifestation of COVID-19: A Case Report
A COVID-19 patient had severe and long-lasting skin issues and unusual hair loss.
research The Rotterdam Study: Objectives And Design Update
The Rotterdam Study investigates diseases in older adults and has produced many research findings.
research Dermatological Adverse Events with Taxane Chemotherapy
Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
research The Imperfect Beauty: Examining the Evolving Concept of Beauty
Modern society values both traditional beauty and imperfections, but media pressures lead to more cosmetic enhancements and ethical concerns.
research Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study
Optimized film improves finasteride skin absorption and treatment efficiency.
research Adjuvant Eflornithine to Maintain IPL-Induced Hair Reduction in Women with Facial Hirsutism: A Randomized Controlled Trial
Topical eflornithine helps maintain hair reduction after IPL therapy in women with facial hirsutism.
research Alopecia Areata: Time for Position Statement to Include New Systemic Therapeutic Advances
New treatments for severe alopecia areata, especially JAK inhibitors, are recommended as first-line therapy.
research Physician Awareness of the Safe Use of Cyproterone Acetate in Europe: A Survey on the Effectiveness of Additional Risk Minimization Measures
Most European physicians know the risks and safe use of Cyproterone acetate, but few remember receiving official safety communications.
research A Comparative Study of Regulations of Cell and Gene Therapy in the US, EU, and India
The US and EU lead in cell and gene therapy regulations with more approvals and clinical trials, while India is in early stages with fewer approvals and expedited processes.
research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis
Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.
research COVID-19 and Endocrine and Metabolic Diseases: An Updated Statement from the European Society of Endocrinology
People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.