Adjuvant Eflornithine to Maintain IPL-Induced Hair Reduction in Women with Facial Hirsutism: A Randomized Controlled Trial

October 2015 in “ Journal of the European Academy of Dermatology and Venereology ”

A.C. Vissing, E. Taudorf, Christina S. Haak, Peter A. Philipsen, Merete Hædersdal

This study investigated the effectiveness of topical eflornithine in maintaining hair reduction in women with facial hirsutism following intense pulsed light (IPL) therapy. Conducted as a randomized, split-face, single-blinded controlled trial, it involved 22 women, with 18 completing the study. Eflornithine was applied twice daily for 6 months to half of the face after 5-6 IPL treatments. Results showed that eflornithine reduced hair regrowth by 14% at 1 month, 9% at 3 months, and 17% at 6 months compared to no treatment. Patients reported satisfaction with the treatment, although two experienced worsening acne. Overall, eflornithine was well tolerated and showed potential as a self-administered option to maintain IPL-induced hair reduction.

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